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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN2131 Questin 3774-64-9 98%
Questin
Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V. harveyi, V. anguillarum, V. cholera...
T17312 (+)-Phenserine 116839-68-0 98%
(+)-Phenserine
(+)-Phenserine is a novel selective inhibitor of cholinesterase non-competitive (IC50: 45.3 μM).
T16353 Meseclazone 29053-27-8 98%
Meseclazone
Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.
TN4426 Leojaponin 864817-63-0 98%
Leojaponin
Leojaponin is a prolyl oligopeptidase (POP) inhibitor. Leojaponin exhibits significant cytoprotective activities against glutamate-induced toxicity at concentrat...
TN3285 8-Hydroxypinoresinol 81426-17-7 98%
8-Hydroxypinoresinol
8-Hydroxypinoresinol has antioxidant activity,it and phillygenin significantly reduce the cell injury by 3-morpholinosydnonimine (SIN-1), a ONOO- generator, may ...
TN4492 Mangostanol 184587-72-2 98%
Mangostanol
Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell l...
TL0018 Lobelin 90-69-7 98%
Lobelin
Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the indu...
TN5193 Tubotaiwine 6711-69-9 98%
Tubotaiwine
Tubotaiwine shows selective activity against L. infantum. Tubotaiwine and apparicine have affinity for adenosine receptors in the micromolar range and also have ...
T14966 Cimetropium Bromide 51598-60-8 98%
Cimetropium Bromide
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
T12825 Timepidium bromide 35035-05-3 98%
Timepidium bromide
Timepidium bromide is an agent of anticholinergic.
TN3287 8-Lavandulylkaempferol 883859-83-4 98%
8-Lavandulylkaempferol
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
T12766 RPR121056 181467-56-1 98%
RPR121056
RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.
TN3550 Buxbodine B 390362-51-3 98%
Buxbodine B
Buxbodine B has weak anti-AChE activity with IC50 values in the range of 10.8-98μM.
T12136 N-0861 racemate 121241-87-0 98%
N-0861 racemate
N-0861 racemate is the racemate of N-0861.
TN3812 Dehydrovomifoliol 39763-33-2 98%
Dehydrovomifoliol
Dehydrovomifoliol could be a marker of Polish heather honey. Dehydrovomifoliol exhibits moderate acetylcholinesterase (AChE) inhibitory activities. Dehydrovomifo...
TN4286 Isodunnianol 139726-30-0 98%
Isodunnianol
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0...
T8306 Epiberberine chloride 889665-86-5 98%
Epiberberine chloride
Epiberberine chloride (Epiberberine (chloride)) is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BA...
T19933 GTS-21 148372-04-7 98%
GTS-21
GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.
TN4600 Myrianthic acid 89786-84-5 98%
Myrianthic acid
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-...
TN3744 Cyclomorusin 62596-34-3 98%
Cyclomorusin
Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of s...
Questin
TN2131
Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V. harveyi, V. anguillarum, V. cholera...
(+)-Phenserine
T17312
(+)-Phenserine is a novel selective inhibitor of cholinesterase non-competitive (IC50: 45.3 μM).
Meseclazone
T16353
Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.
Leojaponin
TN4426
Leojaponin is a prolyl oligopeptidase (POP) inhibitor. Leojaponin exhibits significant cytoprotective activities against glutamate-induced toxicity at concentrat...
8-Hydroxypinoresinol
TN3285
8-Hydroxypinoresinol has antioxidant activity,it and phillygenin significantly reduce the cell injury by 3-morpholinosydnonimine (SIN-1), a ONOO- generator, may ...
Mangostanol
TN4492
Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell l...
Lobelin
TL0018
Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the indu...
Tubotaiwine
TN5193
Tubotaiwine shows selective activity against L. infantum. Tubotaiwine and apparicine have affinity for adenosine receptors in the micromolar range and also have ...
Cimetropium Bromide
T14966
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
Timepidium bromide
T12825
Timepidium bromide is an agent of anticholinergic.
8-Lavandulylkaempferol
TN3287
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
RPR121056
T12766
RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.
Buxbodine B
TN3550
Buxbodine B has weak anti-AChE activity with IC50 values in the range of 10.8-98μM.
N-0861 racemate
T12136
N-0861 racemate is the racemate of N-0861.
Dehydrovomifoliol
TN3812
Dehydrovomifoliol could be a marker of Polish heather honey. Dehydrovomifoliol exhibits moderate acetylcholinesterase (AChE) inhibitory activities. Dehydrovomifo...
Isodunnianol
TN4286
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0...
Epiberberine chloride
T8306
Epiberberine chloride (Epiberberine (chloride)) is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BA...
GTS-21
T19933
GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.
Myrianthic acid
TN4600
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-...
Cyclomorusin
TN3744
Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of s...
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TargetMol