AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.

Cat. No.	Product name	CAS No.	Purity
T3619	VU0357017 hydrochloride	1135242-13-5	99.9%
T3619	VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37...
T10961	Darenzepine	84629-61-8	99.9%
T10961	Darenzepine is a muscarinic receptor inhibitor.
T1657	Varenicline Tartrate	375815-87-5	99.9%
T1657	Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESS...
T1039	Choline chloride	67-48-1	99.89%
T1039	Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, ...
T0804	Pilocarpine Hydrochloride	54-71-7	99.89%
T0804	Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy.
T6478	Donepezil Hydrochloride	120011-70-3	99.89%
T6478	Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
T2191	Tacrine hydrochloride (hydrate)	206658-92-6	99.89%
T2191	Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the eff...
T2984	Scopoletin	92-61-5	99.88%
T2984	Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).
TQ0304	Metixene hydrochloride hydrate	7081-40-5	99.88%
TQ0304	Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 a...
T19940	Sulfoxaflor	946578-00-3	99.87%
T19940	Sulfoxaflor (GF 2032), an agonist of nAChR1 and nAChR2 subtypes, is a systemic insecticide that acts on the central nervous system of insects. Sulfoxaflor is use...
T0287	Hexamethonium Bromide	55-97-0	99.87%
T0287	Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal t...
T14333	Asoxime dichloride	34433-31-3	99.86%
T14333	Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, ...
T2387	Glycopyrrolate	596-51-0	99.86%
T2387	Glycopyrrolate (Glycopyrrolate bromide) is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce saliv...
T22735	DMAB-anabaseine dihydrochloride	154149-38-9	99.86%
T22735	DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing neurona...
T29652	9-Cyclopentyladenine	715-91-3	99.85%
T29652	9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling m...
T21014	Thonzylamine hydrochloride	63-56-9	99.84%
T21014	Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.
T9694	Emraclidine	2170722-84-4	99.84%
T9694	Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T28069	ML380	1627138-52-6	99.84%
T28069	ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
T5S0994	N-Methylcytisine	486-86-2	99.83%
T5S0994	1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethy...
T5655	MAChR-IN-1 hydrochloride	119391-73-0	99.83%
T5655	mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.