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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0999 Clevidipine 167221-71-8 99.86%
Clevidipine
Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pr...
T22735 DMAB-anabaseine dihydrochloride 154149-38-9 99.86%
DMAB-anabaseine dihydrochloride
DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing neurona...
T29652 9-Cyclopentyladenine 715-91-3 99.85%
9-Cyclopentyladenine
9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling m...
T0156 Rocuronium bromide 119302-91-9 99.85%
Rocuronium bromide
Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used t...
T21014 Thonzylamine hydrochloride 63-56-9 99.84%
Thonzylamine hydrochloride
Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.
T77678 TZ3O 2218754-19-7 99.84%
TZ3O
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type ...
T9694 Emraclidine 2170722-84-4 99.84%
Emraclidine
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T28069 ML380 1627138-52-6 99.84%
ML380
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
T15942 MK-7622 1227923-29-6 99.83%
MK-7622
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
T5S0994 N-Methylcytisine 486-86-2 99.83%
N-Methylcytisine
1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethy...
T5655 MAChR-IN-1 hydrochloride 119391-73-0 99.83%
mAChR-IN-1 hydrochloride
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.
T0684 Ribavirin 36791-04-5 99.83%
Ribavirin
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
T33941 PF-03635659 931409-24-4 99.83%
PF-03635659
PF-03635659 is a potent and long dissociative half-life muscarinic M3 antagonist (Ki: 0.2 nM) that shows potential for the treatment of chronic obstructive pulmo...
T7002 Trihexyphenidyl hydrochloride 52-49-3 99.83%
Trihexyphenidyl hydrochloride
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
T22963 McN-A 343 55-45-8 99.82%
McN-A 343
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectivel...
T7555 Piperidolate hydrochloride 129-77-1 99.82%
Piperidolate hydrochloride
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine...
T16411 Otenzepad 102394-31-0 99.81%
Otenzepad
Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.
T3023 Catharanthine sulfate 70674-90-7 99.81%
Catharanthine sulfate
Catharanthine inhibits nicotinic receptor-mediated diaphragm contractions.
T5S0106 Peimisine 19773-24-1 99.8%
Peimisine
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in orde...
T0333 Aniracetam 72432-10-1 99.8%
Aniracetam
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
Clevidipine
T0999
Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pr...
DMAB-anabaseine dihydrochloride
T22735
DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing neurona...
9-Cyclopentyladenine
T29652
9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling m...
Rocuronium bromide
T0156
Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used t...
Thonzylamine hydrochloride
T21014
Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.
TZ3O
T77678
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type ...
Emraclidine
T9694
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
ML380
T28069
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
MK-7622
T15942
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
N-Methylcytisine
T5S0994
1. N-Methylcytisine (Caulophylline)'s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethy...
mAChR-IN-1 hydrochloride
T5655
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.
Ribavirin
T0684
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
PF-03635659
T33941
PF-03635659 is a potent and long dissociative half-life muscarinic M3 antagonist (Ki: 0.2 nM) that shows potential for the treatment of chronic obstructive pulmo...
Trihexyphenidyl hydrochloride
T7002
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
McN-A 343
T22963
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectivel...
Piperidolate hydrochloride
T7555
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine...
Otenzepad
T16411
Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.
Catharanthine sulfate
T3023
Catharanthine inhibits nicotinic receptor-mediated diaphragm contractions.
Peimisine
T5S0106
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in orde...
Aniracetam
T0333
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
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TargetMol