T21153 |
Clothianidin
|
210880-92-5
|
99.73%
|
|
Clothianidin (TI 435), an insecticide, acts as an agonist of acetylcholine to stimulate nAChR, thereby activating post-synaptic acetylcholine receptors but not i...
|
T23286 |
S 24795
|
304679-75-2
|
99.72%
|
|
S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist. S 24795 improves mnemonic function in aged mice and can be used in studies ab...
|
T0162 |
Quetiapine
|
111974-69-7
|
99.71%
|
|
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism ...
|
T6397 |
Atracurium besylate
|
64228-81-5
|
99.71%
|
|
Atracurium besylate (51W89) is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and ...
|
T1327 |
Nortriptyline hydrochloride
|
894-71-3
|
99.71%
|
|
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
|
T1534 |
Darifenacin hydrobromide
|
133099-07-7
|
99.71%
|
|
Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.
|
T80662 |
CDD0102 HCl
|
1196130-86-5
|
99.7%
|
|
CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
|
T61233 |
Penehyclidine hydrochloride
|
151937-76-7
|
99.7%
|
|
Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue. Penehyclidine hydrochloride inhibits the r...
|
T6575 |
LY2119620
|
886047-22-9
|
99.7%
|
|
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.
|
TN1799 |
Isorubrofusarin-6-O-β-gentiobioside
|
200127-93-1
|
99.69%
|
|
Isorubrofusarin-6-O-β-gentiobioside is derived from from Cassia obtusifolia Linn seeds and shows promising inhibitory activity against AChE and BACE1.
|
T2S1181 |
Aloenin
|
38412-46-3
|
99.69%
|
|
1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.
|
T13037 |
Sulindac sulfide
|
49627-27-2
|
99.68%
|
|
Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activati...
|
T4S0111 |
Hupehenine
|
98243-57-3
|
99.68%
|
|
Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic...
|
T2571 |
Benactyzine hydrochloride
|
57-37-4
|
99.68%
|
|
Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in res...
|
T26646 |
AQW051
|
669770-29-0
|
99.67%
|
|
AQW051 (VQW-765) is an orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) specific activator that interacts with recombinant human α7-nAChR expres...
|
T0024 |
Primidone
|
125-33-7
|
99.66%
|
|
Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential ...
|
T1628 |
Rivastigmine tartrate
|
129101-54-8
|
99.66%
|
|
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for t...
|
T4494 |
CLOZAPINE N-OXIDE
|
34233-69-7
|
99.66%
|
|
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD ...
|
T8040 |
Cholesterol myristate
|
1989-52-2
|
99.65%
|
|
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the ...
|
T1285 |
Anethole trithione
|
532-11-6
|
99.65%
|
|
Anethole trithione (Anetholtrithion) is a bile secretion-stimulating drug that restores salivation and relieves the discomfort of dry mouth in chemotherapy-induc...
|