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ATPase

ATPases ( adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion[1][2][3][4][5][6] or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2093L (S)-PF-03716556 928774-44-1 99.66%
(S)-PF-03716556
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
T2405 Revaprazan hydrochloride 178307-42-1 99.64%
Revaprazan hydrochloride
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
T2006 Omecamtiv mecarbil 873697-71-3 99.62%
Omecamtiv mecarbil
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Hear...
T10404 ATP synthase inhibitor 1 1023043-30-2 99.62%
ATP synthase inhibitor 1
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) openin...
T6038 (-)-Blebbistatin 856925-71-8 99.59%
(-)-Blebbistatin
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
T2686L Esomeprazole Sodium 161796-78-7 99.58%
Esomeprazole Sodium
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an ...
T27812 Leminoprazole 104340-86-5 99.56%
Leminoprazole
Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.
T6834 FCCP 370-86-5 99.5%
FCCP
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is of...
T1137 Clorsulon 60200-06-8 99.44%
Clorsulon
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
T1482 Ciclopirox 29342-05-0 99.41%
Ciclopirox
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-...
T2O2668 Oleic acid 112-80-1 99.33%
Oleic acid
Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ AT...
T0114 Trichlormethiazide 133-67-5 99.32%
Trichlormethiazide
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
T6062 Brefeldin A 20350-15-6 99.26%
Brefeldin A
Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation a...
T28136 NC-1300-B 104340-52-5 99.22%
NC-1300-B
NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.
T17313 (+)-SJ733 1424799-20-1 99.21%
(+)-SJ733
(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.
T4190 Ticlopidine 55142-85-3 99.21%
Ticlopidine
Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.
T27371 FR-167356 174185-16-1 99.19%
FR-167356
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
T4861 Trans-Aconitic acid 4023-65-8 99.16%
trans-Aconitic acid
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic acidu...
T2822 Ginsenoside Rb1 41753-43-9 99.12%
Ginsenoside Rb1
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
T13881 Dicirenone 41020-79-5 99.1%
Dicirenone
Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasm...
(S)-PF-03716556
T2093L
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
Revaprazan hydrochloride
T2405
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
Omecamtiv mecarbil
T2006
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Hear...
ATP synthase inhibitor 1
T10404
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) openin...
(-)-Blebbistatin
T6038
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
Esomeprazole Sodium
T2686L
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an ...
Leminoprazole
T27812
Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.
FCCP
T6834
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is of...
Clorsulon
T1137
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
Ciclopirox
T1482
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-...
Oleic acid
T2O2668
Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ AT...
Trichlormethiazide
T0114
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
Brefeldin A
T6062
Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation a...
NC-1300-B
T28136
NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.
(+)-SJ733
T17313
(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.
Ticlopidine
T4190
Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.
FR-167356
T27371
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
trans-Aconitic acid
T4861
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic acidu...
Ginsenoside Rb1
T2822
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
Dicirenone
T13881
Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasm...
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TargetMol