Adenosine Receptor

The adenosine receptors are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. There are four known types of adenosine receptors in humans: A1, A2A, A2B and A3; each is encoded by a different gene.

Cat No.	product name
T0070	Pentoxifylline	Pentoxifylline modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase ...
T1368	Methyl protocatechuate	Methyl protocatechuate is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect.
T1825	Reversine	Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).
T2205	Theophylline-7-acetic acid	Theophylline-7-acetic acid, a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in th...
T2373	Vipadenant	Vipadenant(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM).
T2671	Regadenoson	Regadenoson is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson select...
T6115	Fostamatinib	Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
T6441	CGS 21680 HCl	CGS 21680 HCl（ IC50=22 nM）, an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.
T6552	Istradefylline	Istradefylline(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials s...
T6979	SCH58261	SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.
T7021	ZM241385	ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.
T4265	AZD4635	AZD4635 is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
T4290	Preladenant	Preladenant is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosine receptors.
T6884	2-Cl-IB-MECA	2-Cl-IB-MECA is an adenosine A3 receptor agonist.
T7183	CPI-444	CPI-444 is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.
T7188	Piclidenoson	Piclidenoson, a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.
T7320	Tozadenant	Tozadenant is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)
T7509	PD 117519	PD 117519 is an agonist of adenosine receptor
T7683	Adenosine amine congener	Adenosine amine congener (ADAC) is an agonist of selective A1 adenosine receptor,.
TQ0125	Capadenoson	Capadenoson is a selective adenosine-A1 receptor agonist.
TQ0136	GR 79236	GR79236 is an effective and selective adenosine A1 receptor agonist (Ki: 3.1 nM) that has analgesic and anti-inflammatory actions.
T8312	Derenofylline	Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)
T14078	AB928	AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1].
T14944	CGS 15943	CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Rec...
T13008	ST3932	ST3932 is a ST1535 metabolite, is a adenosine A2A receptor antagonist(Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively).
T11762	Kira8 Hydrochloride	Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
T16158	PF-02575799	PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
T16159	Muramyl dipeptide	Muramyl dipeptide is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dip...
T16281	Nelonicline	Nelonicline is a selective agonist of neuronal nicotinic receptors.
T8598	CHEMBL241987	CHEMBL241987 targets the Adenosine receptor A3 (human)
T8613	1-Ethyl-6-aminouracil	1-Ethyl-6-aminouracil is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenos...
T8512	BAY-545	BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).
T23336	SCH 442416	SCH-442416 is an selective antagonist of adenosine A2A receptor. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0....