Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product name	CAS No.	Purity
T5S0168	Atractylenolide II	73069-14-4	99.89%
T5S0168	1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p...
T3001	Honokiol	35354-74-6	99.87%
T3001	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
T10276	AKT Kinase Inhibitor	842148-40-7	99.86%
T10276	AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.
T8656	CAY10404	340267-36-9	99.85%
T8656	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and M...
T5S0896	Loureirin A	119425-89-7	99.84%
T5S0896	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced p...
T13862	Recilisib	334969-03-8	99.84%
T13862	Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.
T4085	Paris saponin VII	68124-04-9	99.83%
T4085	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T2176	2,3-Butanedione 2-Monoxime	57-71-6	99.83%
T2176	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.
T5508	PF-AKT400	1004990-28-6	99.82%
T5508	PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.
T3844	Deltonin	55659-75-1	99.79%
T3844	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), ...
T1911	Afuresertib	1047644-62-1	99.77%
T1911	Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity...
T11734	K-80003	1292821-90-9	99.76%
T11734	K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.
T3861	Isobavachalcone	20784-50-3	99.76%
T3861	Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in ...
T2798	Esculetin	305-01-1	99.76%
T2798	Esculetin (Cichorigenin) is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema,...
T4S1419	(±)-Praeruptorin A	73069-25-7	99.73%
T4S1419	1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Pr...
T37379	Protectin D1	660430-03-5	99.72%
T37379	Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by neuronal cells and is a potential cardioprotective agent.Protectin D1 attenuates myocardial isch...
T60055	Chromeceptin	331859-86-0	99.72%
T60055	Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.
T17280	(Z)-Guggulsterone	39025-23-5	99.72%
T17280	(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–...
T1952	MK-2206 dihydrochloride	1032350-13-2	99.69%
T1952	MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and sele...
T4444	A-674563 HCl (552325-73-2(free base))	2070009-66-2	99.69%
T4444	A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 ...