T39044 |
Rezvilutamide
|
1572045-62-5
|
99.97%
|
|
Rezvilutamide (SHR3680) is an orally available androgen receptor inhibitor that crosses the blood-brain barrier and has antitumor activity.Rezvilutamide (SHR3680...
|
TN1663 |
Ganoderic acid DM
|
173075-45-1
|
98%
|
|
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 ...
|
T78810 |
BWA-522
|
|
98%
|
|
BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL) an...
|
T78811 |
PROTAC AR-NTD degrader 1
|
|
98%
|
|
PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain...
|
T78945 |
WCA-814
|
|
98%
|
|
WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects in prost...
|
T79024 |
Androgen receptor-IN-5
|
1391944-16-3
|
98%
|
|
Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and...
|
T79156 |
(R)-SKBG-1
|
|
98%
|
|
(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA, ...
|
T79465 |
Anticancer agent 135
|
|
98%
|
|
Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 het...
|
T79519 |
YXG-158
|
2952994-34-0
|
98%
|
|
YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1....
|
T79725 |
ARD-1676
|
2632305-36-1
|
98%
|
|
ARD-1676 is an orally administered androgen receptor (AR) PROTAC degrader that combines an AR ligand with a cereblon ligand. It demonstrates AR-degrading activit...
|
T79891 |
Androgen receptor degrader-3
|
2753650-84-7
|
98%
|
|
Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potential applica...
|
T80633 |
Androgen receptor degrader-1
|
2616553-35-4
|
98%
|
|
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].
|
T80647 |
Androgen receptor degrader-2
|
2616553-33-2
|
98%
|
|
Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].
|
T81662 |
N-Nitrosodicyclohexylamine
|
947-92-2
|
98%
|
|
N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in opposition ...
|
T83119 |
Androgen receptor antagonist 9
|
915086-32-7
|
98%
|
|
Androgen receptor antagonist 9 (compound 28) is an antagonist of the androgen receptor [1].
|
TN1061 |
Ganoderol B
|
104700-96-1
|
98%
|
|
Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate ...
|
T15749 |
LGD-2226
|
328947-93-9
|
98%
|
|
LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle...
|
T10946 |
D4-abiraterone
|
154229-21-7
|
98%
|
|
D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abira...
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
T14675 |
BMS-564929
|
627530-84-1
|
98%
|
|
BMS-564929 is an agonist of androgen receptor (AR, Ki of 2.11±0.16 nM).
|