Androgen Receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

Cat. No.	Product name	CAS No.	Purity
T9035	Testosterone undecanoate	5949-44-0	98.47%
T9035	Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.
T0272	Nilutamide	63612-50-0	98.45%
T0272	Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affi...
T1167	Cyproterone acetate	427-51-0	98.43%
T1167	Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and in...
T8933	JNJ-63576253 free base	2110426-27-0	98.32%
T8933	JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-...
T11410L	GLPG0492	1215085-92-9	98.27%
T11410L	GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic act...
T20761	RU 59063	155180-53-3	98.21%
T20761	RU 59063 is a prototype of a new class of high-affinity nonsteroidal androgen receptor (AR) ligands.
T1596	Chlormadinone acetate	302-22-7	98.18%
T1596	Chlormadinone acetate (Gestafortin) is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
T9752	3-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile	2759137-87-4	98.15%
T9752	3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.
T2207	Adrenosterone	382-45-6	98.13%
T2207	Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.
T13273	UT-34	2168525-92-4	98.1%
T13273	UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-...
TN2245	Sunset Yellow FCF	2783-94-0	98.03%
TN2245	Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used a...
T7440	P,p'-DDE	72-55-9	98%
T7440	p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT
T3393	Triptophenolide	74285-86-2	98%
T3393	Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.
T7358	YK11	1370003-76-1	98%
T7358	YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when use...
T12146	N-Desmethyl-Apalutamide	1332391-11-3	97.83%
T12146	N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
T21740	RD162	915087-27-3	97.74%
T21740	RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
T6400	AZD3514	1240299-33-5	96.6%
T6400	AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
TQ0214	Dimethylcurcumin	52328-98-0	95.77%
TQ0214	Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferatio...
T6002	Enzalutamide	915087-33-1	100%
T6002	Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly u...
T75129	Luxdegalutamide	2750830-09-0	100%
T75129	Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wil...