T12146 |
N-Desmethyl-Apalutamide
|
1332391-11-3
|
97.83%
|
|
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
|
T21740 |
RD162
|
915087-27-3
|
97.74%
|
|
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
|
T6400 |
AZD3514
|
1240299-33-5
|
96.6%
|
|
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
|
TQ0214 |
Dimethylcurcumin
|
52328-98-0
|
95.77%
|
|
Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferatio...
|
T6002 |
Enzalutamide
|
915087-33-1
|
100%
|
|
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly u...
|
T75129 |
Luxdegalutamide
|
2750830-09-0
|
100%
|
|
Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wil...
|
T8117 |
Metenolone acetate
|
434-05-9
|
100%
|
|
Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow ...
|
TN1805 |
Isosilybin B
|
142796-22-3
|
100%
|
|
Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes t...
|
T2991 |
3,3'-Diindolylmethane
|
1968-05-4
|
100%
|
|
3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.
|
T67818 |
BMS-641988
|
|
100%
|
|
BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.
|
T13187 |
Topterone
|
60607-35-4
|
100%
|
|
Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone in cast...
|
T24943 |
VPC-14228
|
19983-28-9
|
98%
|
|
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
|
T8860 |
DSRM-3716
|
58142-99-7
|
98%
|
|
Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a...
|
T39695 |
ARD-2128
|
2222111-87-5
|
98%
|
|
ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protei...
|
TN1067 |
Galloylpaeoniflorin
|
122965-41-7
|
98%
|
|
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibti...
|
T28502 |
Ralaniten
|
1203490-23-6
|
98%
|
|
Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR tran...
|
T2408 |
Ostarine
|
841205-47-8
|
98%
|
|
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, t...
|
T20625 |
Prochloraz
|
67747-09-5
|
98%
|
|
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochlora...
|
T19450 |
N-desmethyl Enzalutamide
|
1242137-16-1
|
98%
|
|
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demon...
|
T8592 |
CTK8A3536
|
926228-58-2
|
98%
|
|
CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.
|