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Apoptosis Apoptosis inducer

Apoptosis inducer

Apoptosis inducers exhibit pro-apoptotic effects through a variety of mechanisms, including DNA cross-linking, inhibition of antiapoptotic proteins and activation of caspases. These inducers may target a specific cellular process in order to induce antitumor or antineoplastic effects.
Cat No. Product Name
T1368 Methyl protocatechuate Thermographic recording material with improved image tone.
T1882 Methylisoindigotin Meisoindigo is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
T2733 Sarsasapogenin Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing p...
T2799 (20S)-Protopanaxadiol (20S)-Protopanaxadiol (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.
T2S1396 3-O-Acetyloleanolic acid 3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G...
T2S2382 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 µM for...
T3008 2-Methoxynaphthoquinone Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well ...
T3299 AT-406 HCl AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 a...
T3488 Tectorigenin Tectorigenin is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation...
T3759 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts a...
T3771 Methyl protodioscin Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl pr...
T3796 Betulinaldehyde Betulinaldehyde has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti...
T3902 Atractylenolide III Atractylenolide III may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potentia...
T3908 10-Gingerol 10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase...
T3916 Ginsenoside F2 Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic...
T4004 Concanavalin A Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.
T4189 4-Oxofenretinide 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
T4241 Rubiadin Rubiadin possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner.
T5011 Manganese chloride Manganese chloride inhibits proliferation in a dose- and time-dependent manner induces G0/G1 and S phase arrest and apoptosis in A549 cells.
T5132 9-dihydro-13-acetylbaccatin III 9-Dihydro-13-acetylbaccatin III is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.
T5514 Epibrassinolide Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a sim...
T5753 Flavokawain C Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the tr...
T5780 HYPOCRELLIN B HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer ...
T5793 Britannin Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
T7337 Kinetin riboside Kinetin riboside can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)
T8282 (-)-Perillyl Alcohol (S)-(−)-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptos...
T8297 Gomisin N Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy a...
TN2103 Procyanidin C1 Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
TN2342 Norkurarinone Norkurarinone is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties, induces MDA-MB-231 and HL-60 cells apoptosis through su...
TQ0016 NKP-1339 NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
TQ0112 Tubulysin A Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antic...
Methyl protocatechuate
T1368CAS 2150-43-8
Thermographic recording material with improved image tone.
Methylisoindigotin
T1882CAS 97207-47-1
Meisoindigo is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
Sarsasapogenin
T2733CAS 126-19-2
Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing p...
(20S)-Protopanaxadiol
T2799CAS 30636-90-9
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.
3-O-Acetyloleanolic acid
T2S1396CAS 4339-72-4
3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G...
3'-Hydroxypterostilbene
T2S2382CAS 475231-21-1
3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 µM for...
2-Methoxynaphthoquinone
T3008CAS 2348-82-5
Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well ...
AT-406 HCl
T3299CAS 1071992-57-8
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 a...
Tectorigenin
T3488CAS 548-77-6
Tectorigenin is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation...
3,4-Dimethoxycinnamic acid
T3759CAS 2316-26-9
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts a...
Methyl protodioscin
T3771CAS 54522-52-0
Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl pr...
Betulinaldehyde
T3796CAS 13159-28-9
Betulinaldehyde has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti...
Atractylenolide III
T3902CAS 73030-71-4
Atractylenolide III may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potentia...
10-Gingerol
T3908CAS 23513-15-7
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase...
Ginsenoside F2
T3916CAS 62025-49-4
Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic...
Concanavalin A
T4004CAS 11028-71-0
Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.
4-Oxofenretinide
T4189CAS 865536-65-8
4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
Rubiadin
T4241CAS 117-02-2
Rubiadin possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner.
Manganese chloride
T5011CAS 7773-01-5
Manganese chloride inhibits proliferation in a dose- and time-dependent manner induces G0/G1 and S phase arrest and apoptosis in A549 cells.
9-dihydro-13-acetylbaccatin III
T5132CAS 142203-65-4
9-Dihydro-13-acetylbaccatin III is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.
Epibrassinolide
T5514CAS 78821-43-9
Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a sim...
Flavokawain C
T5753CAS 37308-75-1
Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the tr...
HYPOCRELLIN B
T5780CAS 123940-54-5
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer ...
Britannin
T5793CAS 33627-28-0
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
Kinetin riboside
T7337CAS 4338-47-0
Kinetin riboside can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)
(-)-Perillyl Alcohol
T8282CAS 18457-55-1
(S)-(−)-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptos...
Gomisin N
T8297CAS 69176-52-9
Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy a...
Procyanidin C1
TN2103CAS 37064-30-5
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
Norkurarinone
TN2342CAS 97938-30-2
Norkurarinone is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties, induces MDA-MB-231 and HL-60 cells apoptosis through su...
NKP-1339
TQ0016CAS 197723-00-5
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
Tubulysin A
TQ0112CAS 205304-86-5
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antic...