T19882 |
Bryonolic acid
|
24480-45-3
|
99.93%
|
|
Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticanc...
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T63228 |
Simmiparib
|
1551355-46-4
|
99.51%
|
|
Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cyc...
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T35528 |
TD52
|
1798328-24-1
|
99.5%
|
|
TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 bindin...
|
T8199 |
(±)-α-Bisabolol
|
515-69-5
|
99.44%
|
|
(±)-α-Bisabolol (Bisabolol) isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, ant...
|
T77732 |
HFY-4A
|
2094810-82-7
|
99.22%
|
|
HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.
|
T10964L |
DB1976 dihydrochloride
|
2369663-93-2
|
99.08%
|
|
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and...
|
T10177 |
(5Z,2E)-CU-3
|
1815598-71-0
|
99.02%
|
|
(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM....
|
T14378 |
AZD5582
|
1258392-53-8
|
98.83%
|
|
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
|
T9175 |
Casein Kinase inhibitor A51
|
2079068-74-7
|
98.42%
|
|
Casein Kinase inhibitor A51 is an orally active casein kinase 1α (CK1α) inhibitor with anticancer activity that induces apoptosis in leukemia cells, and may be u...
|
T11146 |
EC359
|
2012591-09-0
|
98.11%
|
|
EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction...
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
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T3S0541 |
Curzerene
|
17910-09-7
|
|
|
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apopt...
|
TN2091 |
Polygalacin D
|
66663-91-0
|
|
|
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS...
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T1947 |
BS-181
|
1092443-52-1
|
|
|
BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.
|
T3340 |
SCR7
|
1533426-72-0
|
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
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T4S1499 |
Ginsenoside Rk1
|
494753-69-4
|
|
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Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the acti...
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T3081L |
EPZ004777 hydrochloride
|
1380316-03-9
|
|
|
EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
|
T4114 |
Diffractaic Acid
|
436-32-8
|
|
|
Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.
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T4134L |
OTS514
|
1338540-63-8
|
|
|
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed th...
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TN1086 |
Dehydrotrametenolic acid
|
6879-05-6
|
|
|
Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in ...
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