T78586 |
Ac-IETD-CHO
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191338-86-0
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98%
|
|
Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. ...
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T78608 |
Anticancer agent 164
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2235393-30-1
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98%
|
|
CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid ...
|
T78612 |
APPA
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100750-39-8
|
98%
|
|
APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of ...
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T78686 |
Apoptosis inducer 11
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|
98%
|
|
Apoptosis Inducer 11 (compound 3u) promotes apoptosis via the mitochondrial pathway and elicits a G2/M block alongside a marked reduction in the S phase within n...
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T78742 |
Anticancer agent 132
|
|
98%
|
|
Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities. It also arrests the c...
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T78743 |
Anticancer agent 133
|
|
98%
|
|
Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy. Additionally, it suppresses...
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T78764 |
Anticancer agent 136
|
|
98%
|
|
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and b...
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T78846 |
EP12
|
2882916-73-4
|
98%
|
|
EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupti...
|
T78904 |
Anticancer agent 110
|
887349-03-3
|
98%
|
|
Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells at...
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T78909 |
Antitumor agent-97
|
2654024-16-3
|
98%
|
|
Antitumor agent-97 (compound 42), an anticancer agent, effectively inhibits proliferation and autophagy in MGC 803 cells, induces apoptosis, and enhances ROS acc...
|
T78911 |
Antitumor agent-112
|
|
98%
|
|
Antitumor agent-112 (compound 3a) is a potent antitumor agent that induces apoptosis and exhibits cytotoxic activity on A549 cells, with an IC50 value of 91.35 μ...
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T78912 |
Antitumor agent-113
|
|
98%
|
|
Antitumor Agent-113 exhibits cytotoxicity in A549 cells, with an IC50 of 46.60 μM, and induces apoptosis, making it applicable for research in non-small cell lun...
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T78940 |
EGFR-IN-78
|
|
98%
|
|
EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, serves as a reversible EGFR C797S-TK inhibitor and an apoptosis inducer. It exhibits anti-proliferative...
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T78941 |
Anticancer agent 130
|
|
98%
|
|
Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].
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T78957 |
Anticancer agent 105
|
2450987-57-0
|
98%
|
|
Anticancer agent 105, a thienopyrimidine scaffold-based compound, exhibits selective toxicity towards melanoma and induces apoptosis. Additionally, it significan...
|
T78958 |
Anticancer agent 106
|
|
98%
|
|
Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, su...
|
T78970 |
Antitumor agent-96
|
|
98%
|
|
"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the en...
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T78982 |
BK60106
|
|
98%
|
|
BK60106, a CD99 inhibitor, selectively targets and binds to the extracellular domain of CD99, effectively inducing apoptosis in Ewing sarcoma (ES) cells with min...
|
T79224 |
Ara-SH
|
|
98%
|
|
Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded Cytarabine and...
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T79289 |
Antiproliferative agent-27
|
|
98%
|
|
Antiproliferative Agent-27 (Compound 11) is a notable antiproliferative agent that markedly diminishes tumor cell colony formation and induces apoptosis, demonst...
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