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Apoptosis

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T41288 Myristoleic acid 544-64-9 99.65%
Myristoleic acid
Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human pro...
T1890 Pracinostat 929016-96-6 99.65%
Pracinostat
Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral do...
TN4673 (+)-Nortrachelogenin 61521-74-2 99.64%
(+)-Nortrachelogenin
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
T0649 Salicylic acid 69-72-7 99.64%
Salicylic acid
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
T2145 Temsirolimus 162635-04-3 99.64%
Temsirolimus
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
T6308 Stattic 19983-44-9 99.64%
Stattic
Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has a...
T4036 Solasodine 126-17-0 99.64%
Solasodine
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cyt...
T6928 Pantoprazole 102625-70-7 99.63%
Pantoprazole
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
T14371 Barasertib 722543-31-9 99.63%
Barasertib
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
T16901 SMIP004 143360-00-3 99.63%
SMIP004
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
T3S1227 Aristolactam I 13395-02-3 99.63%
Aristolactam I
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristolo...
T3094 PS-1145 431898-65-6 99.63%
PS-1145
PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.
T8461 SKI V 24418-86-8 99.62%
SKI V
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces...
T3151 Brassinolide 72962-43-7 99.62%
Brassinolide
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
T6539 Ibandronate sodium monohydrate 138926-19-9 99.62%
Ibandronate sodium monohydrate
Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
T5765 Ranaconitine 1360-76-5 99.62%
ranaconitine
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
T77650 Topoisomerase II inhibitor 14 305343-00-4 99.62%
Topoisomerase II inhibitor 14
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis a...
T14973 CITCO 338404-52-7 99.62%
CITCO
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear ...
T7016 VR23 1624602-30-7 99.62%
VR23
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for ca...
T30998L COG-1410 acetate 99.61%
COG-1410 acetate
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
Myristoleic acid
T41288
Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human pro...
Pracinostat
T1890
Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral do...
(+)-Nortrachelogenin
TN4673
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
Salicylic acid
T0649
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
Temsirolimus
T2145
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
Stattic
T6308
Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has a...
Solasodine
T4036
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cyt...
Pantoprazole
T6928
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
Barasertib
T14371
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
SMIP004
T16901
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
Aristolactam I
T3S1227
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristolo...
PS-1145
T3094
PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.
SKI V
T8461
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces...
Brassinolide
T3151
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
Ibandronate sodium monohydrate
T6539
Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
ranaconitine
T5765
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
Topoisomerase II inhibitor 14
T77650
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis a...
CITCO
T14973
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear ...
VR23
T7016
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for ca...
COG-1410 acetate
T30998L
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
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TargetMol