T78941 |
Anticancer agent 130
|
|
98%
|
|
Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].
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T78957 |
Anticancer agent 105
|
2450987-57-0
|
98%
|
|
Anticancer agent 105, a thienopyrimidine scaffold-based compound, exhibits selective toxicity towards melanoma and induces apoptosis. Additionally, it significan...
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T78958 |
Anticancer agent 106
|
|
98%
|
|
Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, su...
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T78970 |
Antitumor agent-96
|
|
98%
|
|
"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the en...
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T78982 |
BK60106
|
|
98%
|
|
BK60106, a CD99 inhibitor, selectively targets and binds to the extracellular domain of CD99, effectively inducing apoptosis in Ewing sarcoma (ES) cells with min...
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T79224 |
Ara-SH
|
|
98%
|
|
Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded Cytarabine and...
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T79289 |
Antiproliferative agent-27
|
|
98%
|
|
Antiproliferative Agent-27 (Compound 11) is a notable antiproliferative agent that markedly diminishes tumor cell colony formation and induces apoptosis, demonst...
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T79332 |
Antiproliferative agent-32
|
2925814-05-5
|
98%
|
|
Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells, ...
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T79434 |
Antitumor agent-103
|
|
98%
|
|
Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties. This compound halts the cell cycle at ...
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T79453 |
Anticancer agent 134
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|
98%
|
|
Anticancer Agent 134 (Compound 6a), an environment-sensitive fluorescent probe, induces apoptosis and selectively differentiates between tumor and normal tissues...
|
T79463 |
Antitumor agent-110
|
2563879-93-4
|
98%
|
|
Antitumor Agent-110 (Compound 13), an imidazotetrazine anticancer agent, exhibits excellent permeability. It halts the cell cycle at the G2/M phase and induces a...
|
T79474 |
GSPT1 degrader-1
|
|
98%
|
|
GSPT1 Degrader-1 (Compound 9q) effectively facilitates the degradation of G1 to S phase transition 1 (GSPT1) through the ubiquitin-proteasome system and induces ...
|
T79478 |
Anti-inflammatory agent 45
|
|
98%
|
|
Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies, su...
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T79557 |
Fac-[Re(CO)3(L6)(H2O)][NO3]
|
|
98%
|
|
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits c...
|
T79580 |
Antitumor agent-115
|
2759277-20-6
|
98%
|
|
Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line. It imped...
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T79646 |
Anticancer agent 153
|
|
98%
|
|
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Pote...
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T79664 |
RUNX-IN-1
|
2177285-35-5
|
98%
|
|
RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their specif...
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T79665 |
RUNX-IN-2
|
2893777-88-1
|
98%
|
|
RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibiting ...
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T79669 |
FD2157
|
|
98%
|
|
FD2157, a photosensitive PI3K inhibitor, exhibits inhibitory IC50 values of 43 nM for PI3Kα, 83 nM for PI3Kβ, 84 nM for PI3Kγ, and 14 nM for PI3Kδ. Upon exposure...
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T79699 |
Anti-TNBC agent-2
|
2422001-22-5
|
98%
|
|
Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic. It promotes apoptosis in MDA-MB-231 cells, while a...
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