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Endocrinology/Hormones Aromatase

Aromatase

Aromatase is the enzyme that catalyzes a key aromatization step in the synthesis of estrogen. It converts the enone ring of androgen precursors such as testosterone, to a phenol, completing the synthesis of estrogen.
Cat No. product name
T0393 Anastrozole Anastrozole(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis.
T1099 Formestane Formestane is a selective aromatase inhibitor(IC50=80 nM) with antineoplastic activity.
T1103 Aminoglutethimide Aminoglutethimide, an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
T1587 Exemestane Exemestane is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
T1590 Letrozole Letrozole is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
T1692 3,4-Dimethoxyhydrocinnamic acid It is an organic compund with molecular fomula C11H14O4.
T6917 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf.
T2O2744 alpha-Naphthoflavone Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
T7197 Fadrozole Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
T7556 Fadrozole hydrochloride Fadrozole hydrochloride is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
T3390 Obacunone Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead comp...
T12319 Org30958 Org30958 is a potent inhibitor of aromatase in vivo.
T10321 Androsta-1,4,6-triene-3,17-dione Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor (Ki: 0.18 μM). It inhibits estrogen biosynthesis and shows antifertility effe...
T21311 Testolactone Testolactone is an aromatase inhibitor, blocks conversion of androgens to estrogens.It is progesterone derivative with antineoplastic activity. Testolactone in...
Anastrozole
T0393CAS 120511-73-1
Anastrozole(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis.
Formestane
T1099CAS 566-48-3
Formestane is a selective aromatase inhibitor(IC50=80 nM) with antineoplastic activity.
Aminoglutethimide
T1103CAS 125-84-8
Aminoglutethimide, an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
Exemestane
T1587CAS 107868-30-4
Exemestane is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
Letrozole
T1590CAS 112809-51-5
Letrozole is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
3,4-Dimethoxyhydrocinnamic acid
T1692CAS 2107-70-2
It is an organic compund with molecular fomula C11H14O4.
Oleuropein
T6917CAS 32619-42-4
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
alpha-Naphthoflavone
T2O2744CAS 604-59-1
Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
Fadrozole
T7197CAS 102676-47-1
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
Fadrozole hydrochloride
T7556CAS 102676-31-3
Fadrozole hydrochloride is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
Obacunone
T3390CAS 751-03-1
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead comp...
Org30958
T12319CAS 99957-90-1
Org30958 is a potent inhibitor of aromatase in vivo.
Androsta-1,4,6-triene-3,17-dione
T10321CAS 633-35-2
Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor (Ki: 0.18 μM). It inhibits estrogen biosynthesis and shows antifertility effe...
Testolactone
T21311CAS 968-93-4
Testolactone is an aromatase inhibitor, blocks conversion of androgens to estrogens.It is progesterone derivative with antineoplastic activity. Testolactone in...