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Aromatase

Aromatase is the enzyme that catalyzes a key aromatization step in the synthesis of estrogen. It converts the enone ring of androgen precursors such as testosterone, to a phenol, completing the synthesis of estrogen.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN3987 Eriodictyol chalcone 14917-41-0 98%
Eriodictyol chalcone
Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.
T12319 Org30958 99957-90-1 98%
Org30958
Org30958 is a potent inhibitor of aromatase in vivo.
T0530 Flavanone 487-26-3 99.95%
Flavanone
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interve...
T26322 Vorozole 129731-10-8 99.89%
Vorozole
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the...
T1587 Exemestane 107868-30-4 99.73%
Exemestane
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
T1692 3-(3,4-Dimethoxyphenyl)propanoic acid 2107-70-2 99.68%
3-(3,4-Dimethoxyphenyl)propanoic acid
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression ...
T1590 Letrozole 112809-51-5 99.68%
Letrozole
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
T4281 Endoxifen 110025-28-0 99.66%
Endoxifen
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It ...
T27918 LY 43578 26766-35-8 99.62%
LY 43578
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (I...
T6917 Oleuropein 32619-42-4 99.16%
Oleuropein
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
T71708 Minamestane 105051-87-4 99.04%
Minamestane
Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes ...
T2O2744 Alpha-Naphthoflavone 604-59-1 98%
alpha-Naphthoflavone
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
T7197 Fadrozole 102676-47-1 98%
Fadrozole
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
T26322L (-)-Vorozole 132042-69-4 97.14%
(-)-Vorozole
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
T23549 YM 511 148869-05-0 100%
YM 511
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
T27320 Finrozole 160146-17-8 100%
Finrozole
Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.
T3899 Calceolarioside B 105471-98-5 100%
Calceolarioside B
Calceolarioside B (Desrhamnosyl isoacteoside) displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.
T1103 Aminoglutethimide 125-84-8 98%
Aminoglutethimide
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
T7556 Fadrozole hydrochloride 102676-31-3 98%
Fadrozole hydrochloride
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
T0393 Anastrozole 120511-73-1 98%
Anastrozole
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesi...
Eriodictyol chalcone
TN3987
Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.
Org30958
T12319
Org30958 is a potent inhibitor of aromatase in vivo.
Flavanone
T0530
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interve...
Vorozole
T26322
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the...
Exemestane
T1587
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
3-(3,4-Dimethoxyphenyl)propanoic acid
T1692
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression ...
Letrozole
T1590
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
Endoxifen
T4281
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It ...
LY 43578
T27918
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (I...
Oleuropein
T6917
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
Minamestane
T71708
Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes ...
alpha-Naphthoflavone
T2O2744
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
Fadrozole
T7197
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
(-)-Vorozole
T26322L
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
YM 511
T23549
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
Finrozole
T27320
Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.
Calceolarioside B
T3899
Calceolarioside B (Desrhamnosyl isoacteoside) displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.
Aminoglutethimide
T1103
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
Fadrozole hydrochloride
T7556
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
Anastrozole
T0393
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesi...
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