T0847 |
Chenodeoxycholic acid
|
474-25-9
|
99.97%
|
|
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorpti...
|
T1149 |
Fenofibrate
|
49562-28-9
|
99.97%
|
|
Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyp...
|
T3155 |
SMER28
|
307538-42-7
|
99.97%
|
|
SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells via an mTOR-independent mechanism and p...
|
T0747 |
Sulfathiazole
|
72-14-0
|
99.97%
|
|
Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.
|
T3045 |
Salubrinal
|
405060-95-9
|
99.97%
|
|
Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).
|
T2187 |
Orthanilamide
|
3306-62-5
|
99.96%
|
|
Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.
|
T2509 |
Tozasertib
|
639089-54-6
|
99.96%
|
|
Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C). It shows selectivity against more than 190 different k...
|
T15806 |
LY2562175
|
1103500-20-4
|
99.96%
|
|
LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).
|
T6671 |
Sirtinol
|
410536-97-9
|
99.96%
|
|
Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
|
T1330 |
Acitretin
|
55079-83-9
|
99.95%
|
|
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
|
T0920 |
Ambroxol
|
18683-91-5
|
99.95%
|
|
Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of...
|
T6994 |
SR12813
|
126411-39-0
|
99.95%
|
|
SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.
|
T0687 |
Simvastatin
|
79902-63-9
|
99.95%
|
|
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cho...
|
T6087 |
AZD 6482
|
1173900-33-8
|
99.95%
|
|
AZD 6482 (AZD6482) is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.
|
T2220 |
2-Methoxyestradiol
|
362-07-2
|
99.95%
|
|
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by red...
|
T1569 |
Tigecycline
|
220620-09-7
|
99.94%
|
|
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering...
|
T2355 |
CFTR(inh)-172
|
307510-92-5
|
99.94%
|
|
CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.
|
T2492 |
Perifosine
|
157716-52-4
|
99.94%
|
|
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
|
T17209 |
UVI 3003
|
847239-17-2
|
99.94%
|
|
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respective...
|
T6151 |
GW 501516
|
317318-70-0
|
99.94%
|
|
GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.
|