TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
TN4490 |
Manassantin B
|
88497-88-5
|
98%
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV ...
|
T14499 |
Bax activator-1
|
1638526-94-9
|
98%
|
|
Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].
|
TN1139 |
Dehydrocavidine
|
83218-34-2
|
98%
|
|
Dehydrocavidine (Dehydrocorydaline) has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activati...
|
TN3931 |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
|
57719-81-0
|
98%
|
|
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular ...
|
TN3653 |
Cimidahurinine
|
142542-89-0
|
98%
|
|
Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity...
|
T10485 |
PROTAC Bcl2 degrader-1
|
2378801-85-3
|
98%
|
|
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
|
TN2040 |
Panaxynol
|
81203-57-8
|
98%
|
|
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.
|
TN4307 |
Isolimonexic acid
|
73904-93-5
|
98%
|
|
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
|
T5526 |
Glycoborinine
|
233279-39-5
|
98%
|
|
Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-ac...
|
T13337 |
WEHI-539 hydrochloride
|
2070018-33-4
|
98%
|
|
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
|
T13337L |
WEHI-539
|
1431866-33-9
|
98%
|
|
WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
|
TN4271 |
Isochamaejasmine
|
93859-63-3
|
98%
|
|
Isochamaejasmine, isolated from S. chamaejasme L., inhibits NF-κB activation. Isochamaejasmine induces leukemia cell apoptosis by inhibiting the activity of Bcl-...
|
TN3614 |
Cearoin
|
52811-37-7
|
98%
|
|
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
|
TN2308 |
Wilfortrine
|
37239-48-8
|
98%
|
|
Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic ...
|
TMA0153 |
Safflor Yellow A
|
85532-77-0
|
98%
|
|
Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis.
|
T11973 |
Mcl1-IN-11
|
2042211-13-0
|
98%
|
|
Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.
|
T10577 |
BM 957
|
1391107-54-2
|
98%
|
|
BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM).
|
T16043 |
Metaproterenol
|
586-06-1
|
98%
|
|
Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).
|
TN3486 |
Bakkenolide IIIa
|
915289-60-0
|
98%
|
|
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB...
|