Home Tools
Log in
Cart

Beta Amyloid

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T37621 Ezeprogind disulfate 1616671-13-6 99.87%
Ezeprogind disulfate
Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind d...
TN1116 Schisandrone 98619-25-1 99.84%
Schisandrone
Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.
T6202 DAPT 208255-80-5 99.81%
DAPT
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces ...
T1637 Deferoxamine Mesylate 138-14-7 99.8%
Deferoxamine Mesylate
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
T21470L Davunetide acetate 99.78%
Davunetide acetate
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing pept...
T2872 Ginsenoside Re 52286-59-6 99.78%
Ginsenoside Re
Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
TN1725 Hederacolchiside E 33783-82-3 99.78%
Hederacolchiside E
Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchisid...
T6495 EUK-134 81065-76-1 99.78%
EUK-134
EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amy...
T3394 Timosaponin BII 136656-07-0 99.77%
Timosaponin BII
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activ...
T4422 Edonerpic maleate 519187-97-4 99.73%
Edonerpic maleate
Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
T3914 Saikosaponin C 20736-08-7 99.71%
Saikosaponin C
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
TN2211 Silybin B 142797-34-0 99.66%
Silybin B
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silym...
TP1214L β-Amyloid 15-21 acetate TP1214L 99.62%
β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is i...
T61439 DSS30 883027-32-5 99.61%
DSS30
DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl), which reduces the secretion of...
T4077 PE859 1402727-29-0 99.6%
PE859
PE859 is a potent inhibitor of both tau and Aβ aggregation.
T63540 Astrophloxine 14696-39-0 99.57%
Astrophloxine
Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal...
T2961 Notoginsenoside R1 80418-24-2 99.57%
Notoginsenoside R1
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
T3521 γ-Secretase-IN-1 209986-17-4 99.56%
γ-Secretase-IN-1
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and...
T10782 CGP52411 145915-58-8 99.56%
CGP52411
CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramati...
T11043 Dihydroergocristine mesylate 24730-10-7 99.51%
Dihydroergocristine mesylate
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomati...
Ezeprogind disulfate
T37621
Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind d...
Schisandrone
TN1116
Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.
DAPT
T6202
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces ...
Deferoxamine Mesylate
T1637
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
Davunetide acetate
T21470L
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing pept...
Ginsenoside Re
T2872
Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
Hederacolchiside E
TN1725
Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchisid...
EUK-134
T6495
EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amy...
Timosaponin BII
T3394
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activ...
Edonerpic maleate
T4422
Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
Saikosaponin C
T3914
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
Silybin B
TN2211
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silym...
β-Amyloid 15-21 acetate
TP1214L
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is i...
DSS30
T61439
DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl), which reduces the secretion of...
PE859
T4077
PE859 is a potent inhibitor of both tau and Aβ aggregation.
Astrophloxine
T63540
Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal...
Notoginsenoside R1
T2961
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
γ-Secretase-IN-1
T3521
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and...
CGP52411
T10782
CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramati...
Dihydroergocristine mesylate
T11043
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomati...
1 2 3 4 5
TargetMol