CaMK

CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca2+) and calmodulin. When activated, the enzymes transfer phosphates from ATP to defined serine or threonine residues in other proteins, so they are serine/threonine-specific protein kinases. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms involved in the learning and memory of an organism.There are 2 common types of CAM Kinase proteins: specialized and multi-functional CAM kinases.

Cat. No.	Product name	CAS No.	Purity
T8389	Trifluoperazine	117-89-5	99.03%
T8389	Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
T3546	STO-609	52029-86-4	98.95%
T3546	STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL)....
T23525	W-9 hydrochloride	69762-85-2	98.9%
T23525	W-9 hydrochloride is a calmodulin antagonist.
T2694	KN-62	127191-97-3	98.77%
T2694	KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.
T1659	Melatonin	73-31-4	98.71%
T1659	Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in...
T23522	W-13 hydrochloride	88519-57-7	98.51%
T23522	W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.
T68064	Elziverine	95520-81-3	98.43%
T68064	Elziverine is an orally available small molecule calmodulin antagonist.Elziverine in vitro treatment inhibited Ca-loading-induced acanthocyte formation in SHRSP,...
T14860	CaMKII-IN-1	1208123-85-6	98.35%
T14860	CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, p38a, MLCK, Akt1, and PKC.
TN1008	Psoralenoside	905954-17-8	98.17%
TN1008	Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activi...
T10667	Calmidazolium chloride	57265-65-3	98.06%
T10667	Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induc...
T1158	Phenoxybenzamine hydrochloride	63-92-3	98.04%
T1158	Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihyp...
TP1217L	Autocamtide 2 TFA(129198-88-5 free base)	TP1217L	98%
TP1217L	Autocamtide 2 TFA is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). Autocamtide 2 TFA can be used in the CaMKII...
T4185	Lavendustin C	125697-93-0	97.77%
T4185	lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
TQ0137	A-484954	142557-61-7	97.47%
TQ0137	A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.
TP1921L1	Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)	TP1921L1	97.03%
TP1921L1	Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibit...
TP1271L	Calmodulin-Dependent Protein Kinase II 290-309 acetate		96.7%
TP1271L	Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).
T2159	CaMKP Inhibitor	52789-62-5	96.55%
T2159	CaMKP Inhibitor can inhibit CaMKP.
TP1216	CaM kinase II inhibitor TFA salt	TP1216	100%
TP1216	CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
T1222	Trifluoperazine dihydrochloride	440-17-5	100%
T1222	Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
T16791	Rottlerin	82-08-6
T16791	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKC...