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Membrane transporter/Ion channel Calcium Channel

Calcium Channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels.
Cat No. product name
T0077 Dantrolene sodium salt Dantrolene is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity ...
T0112 Diltiazem hydrochloride Diltiazem Hydrochloride is a benzothiazepine calcium channel blocking agent with vasodilating action due to its antagonism of the actions of CALCIUM ion on memb...
T0119 Nitrendipine Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel block...
T0121 Azelnidipine Azelnidipine is a dihydropyridine used as calcium channel blocker.
T0145 Felodipine Felodipine is a longlasting 1,4-dihydropyridine calcium channel repressor.
T0163 Nisoldipine Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
T0192 Levetiracetam Levetiracetam is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levet...
T0193 Manidipine dihydrochloride Manidipine dihydrochloride is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).
T0207 Ranolazine dihydrochloride Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), an...
T0231 Amlodipine Besylate Amlodipine Besylate is a long-lasting calcium channel blocker.
T0267 Zonisamide Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydr...
T0283 Trimethadione Trimethadione is a dione-type anticonvulsant with antiepileptic activity.
T0327 Fendiline hydrochloride Fendiline is a non-selective blocker of calcium channel.
T0343 Nimodipine Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T0388 Cilnidipine Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
T0728 Ethosuximide Ethosuximide is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other type...
T0806 Flunarizine dihydrochloride Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective i...
T0903 Stugeron Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it ind...
T0957 Isradipine Isradipine is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calci...
T0999 Clevidipine butyrate Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when ...
T1010 Verapamil hydrochloride Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.
T1073 Dronedarone hydrochloride Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T1146 Nifedipine Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and v...
T1197 Trimebutine maleate Trimebutine maleate is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors se...
T1215 Nicardipine hydrochloride Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nica...
T1234 5,5-Dimethyloxazolidine-2,4-dione An anticonvulsant that is the active metabolite of TRIMETHADIONE.
T1385 Amlodipine Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
T1422 Nilvadipine Nilvadipine, a calcium channel blocker (CCB), is utilized for treatment of hypertension.
T1435 Praziquantel Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid c...
T1439 Lacidipine Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does ...
T1474 Otilonium bromide Otilonium Bromide, an antimuscarinic, is utilized as a spasmolytic agent.
T1545 (S)-Amlodipine Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantio...
T1641 Strontium ranelate Strontium ranelate, a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis ...
T1730 NPS 2143 NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor.
T2323 Efonidipine Efonidipine(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
T2519 Lercanidipine Lercanidipine is a calcium channel blocker of the dihydropyridine class.
T2604 1-Ethyl-2-benzimidazolinone 1-Ethyl-2-benzimidazolinone is a calium channel agonist.
T2996 Tetrandrine Tetrandrine is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and...
T3377 phenylalanine Phenylalanine is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.
T3484 (±)-trans-ACPD (±)-trans-ACPD is an equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor);...
T3508 SEA-0400 SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger.
T3543 NS 638 NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
T3703 ABT-639 ABT-639 is a potent and selective T-type calcium channel blocker.
T6571 Lomerizine hydrochloride Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
T6577 Manidipine Manidipine, a calcium channel blocker, which is dihydropyridine type. It is utilized
T6633 Ranolazine Ranolazine 2HCl,a calcium uptake inhibitor,is used to treat chronic angina via the sodium/calcium channa.
T6777 Bay K 8644 Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
T6874 Lercanidipine hydrochloride Lercanidipine is a calcium channel blocker of the dihydropyridine class.
T4284 (S)-Amlodipine Besylate (103129-82-4(free base)) Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipin...
TCS0102 Pulegone 1. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a...
Dantrolene sodium salt
T0077CAS 14663-23-1
Dantrolene is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity ...
Diltiazem hydrochloride
T0112CAS 33286-22-5
Diltiazem Hydrochloride is a benzothiazepine calcium channel blocking agent with vasodilating action due to its antagonism of the actions of CALCIUM ion on memb...
Nitrendipine
T0119CAS 39562-70-4
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel block...
Azelnidipine
T0121CAS 123524-52-7
Azelnidipine is a dihydropyridine used as calcium channel blocker.
Felodipine
T0145CAS 72509-76-3
Felodipine is a longlasting 1,4-dihydropyridine calcium channel repressor.
Nisoldipine
T0163CAS 63675-72-9
Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
Levetiracetam
T0192CAS 102767-28-2
Levetiracetam is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levet...
Manidipine dihydrochloride
T0193CAS 89226-75-5
Manidipine dihydrochloride is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).
Ranolazine dihydrochloride
T0207CAS 95635-56-6
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), an...
Amlodipine Besylate
T0231CAS 111470-99-6
Amlodipine Besylate is a long-lasting calcium channel blocker.
Zonisamide
T0267CAS 68291-97-4
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydr...
Trimethadione
T0283CAS 127-48-0
Trimethadione is a dione-type anticonvulsant with antiepileptic activity.
Fendiline hydrochloride
T0327CAS 13636-18-5
Fendiline is a non-selective blocker of calcium channel.
Nimodipine
T0343CAS 66085-59-4
Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
Cilnidipine
T0388CAS 132203-70-4
Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
Ethosuximide
T0728CAS 77-67-8
Ethosuximide is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other type...
Flunarizine dihydrochloride
T0806CAS 30484-77-6
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective i...
Stugeron
T0903CAS 298-57-7
Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it ind...
Isradipine
T0957CAS 75695-93-1
Isradipine is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calci...
Clevidipine butyrate
T0999CAS 167221-71-8
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when ...
Verapamil hydrochloride
T1010CAS 152-11-4
Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.
Dronedarone hydrochloride
T1073CAS 141625-93-6
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
Nifedipine
T1146CAS 21829-25-4
Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and v...
Trimebutine maleate
T1197CAS 34140-59-5
Trimebutine maleate is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors se...
Nicardipine hydrochloride
T1215CAS 54527-84-3
Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nica...
5,5-Dimethyloxazolidine-2,4-dione
T1234CAS 695-53-4
An anticonvulsant that is the active metabolite of TRIMETHADIONE.
Amlodipine
T1385CAS 88150-42-9
Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
Nilvadipine
T1422CAS 75530-68-6
Nilvadipine, a calcium channel blocker (CCB), is utilized for treatment of hypertension.
Praziquantel
T1435CAS 55268-74-1
Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid c...
Lacidipine
T1439CAS 103890-78-4
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does ...
Otilonium bromide
T1474CAS 26095-59-0
Otilonium Bromide, an antimuscarinic, is utilized as a spasmolytic agent.
(S)-Amlodipine
T1545CAS 103129-82-4
Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantio...
Strontium ranelate
T1641CAS 135459-87-9
Strontium ranelate, a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis ...
NPS 2143
T1730CAS 284035-33-2
NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor.
Efonidipine
T2323CAS 111011-63-3
Efonidipine(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
Lercanidipine
T2519CAS 100427-26-7
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
1-Ethyl-2-benzimidazolinone
T2604CAS 10045-45-1
1-Ethyl-2-benzimidazolinone is a calium channel agonist.
Tetrandrine
T2996CAS 518-34-3
Tetrandrine is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and...
phenylalanine
T3377CAS 63-91-2
Phenylalanine is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.
(±)-trans-ACPD
T3484CAS 67684-64-4
(±)-trans-ACPD is an equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor);...
SEA-0400
T3508CAS 223104-29-8
SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger.
NS 638
T3543CAS 150493-34-8
NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
ABT-639
T3703CAS 1235560-28-7
ABT-639 is a potent and selective T-type calcium channel blocker.
Lomerizine hydrochloride
T6571CAS 101477-54-7
Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
Manidipine
T6577CAS 89226-50-6
Manidipine, a calcium channel blocker, which is dihydropyridine type. It is utilized
Ranolazine
T6633CAS 95635-55-5
Ranolazine 2HCl,a calcium uptake inhibitor,is used to treat chronic angina via the sodium/calcium channa.
Bay K 8644
T6777CAS 71145-03-4
Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
Lercanidipine hydrochloride
T6874CAS 132866-11-6
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
(S)-Amlodipine Besylate (103129-82-4(free base))
T4284CAS T4284
Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipin...
Pulegone
TCS0102CAS 89-82-7
1. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a...