T5114 |
Pyridaben
|
96489-71-3
|
99.75%
|
|
Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).
|
T8143 |
Bevantolol hydrochloride
|
42864-78-8
|
99.74%
|
|
Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
|
T4S1419 |
(±)-Praeruptorin A
|
73069-25-7
|
99.73%
|
|
1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Pr...
|
T76373L |
Ser-Ala-alloresact acetate
|
|
99.73%
|
|
Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.
|
T25372 |
EMD57033
|
147527-31-9
|
99.72%
|
|
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
|
TQ0139 |
VU 0240551
|
893990-34-6
|
99.72%
|
|
VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
|
T0728 |
Ethosuximide
|
77-67-8
|
99.72%
|
|
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by ...
|
T12032 |
Mibefradil dihydrochloride
|
116666-63-8
|
99.72%
|
|
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type ...
|
T0858 |
Flufenamic acid
|
530-78-9
|
99.71%
|
|
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
|
T41190 |
AY 77
|
1835734-92-3
|
99.7%
|
|
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
|
T3904 |
Gomisin J
|
66280-25-9
|
99.69%
|
|
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
|
T12204 |
NecroX-5
|
1383718-29-3
|
99.68%
|
|
NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.
|
T6541 |
Ibutilide Fumarate
|
122647-32-9
|
99.68%
|
|
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
|
TN1721 |
Gypenoside L
|
94987-09-4
|
99.65%
|
|
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also i...
|
T16339 |
Norverapamil hydrochloride
|
67812-42-4
|
99.63%
|
|
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel...
|
T0916 |
Butamben
|
94-25-7
|
99.61%
|
|
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
|
TQ0033 |
Zegocractin
|
1713240-67-5
|
99.59%
|
|
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.
|
T6227 |
Benidipine hydrochloride
|
91599-74-5
|
99.56%
|
|
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
|
T21454 |
Nicardipine
|
55985-32-5
|
99.56%
|
|
Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
|
T0343 |
Nimodipine
|
66085-59-4
|
99.56%
|
|
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
|