T0858 |
Flufenamic acid
|
530-78-9
|
99.71%
|
|
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
|
T0343 |
Nimodipine
|
66085-59-4
|
99.71%
|
|
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
|
T41190 |
AY 77
|
1835734-92-3
|
99.7%
|
|
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
|
T3904 |
Gomisin J
|
66280-25-9
|
99.69%
|
|
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
|
T12204 |
NecroX-5
|
1383718-29-3
|
99.68%
|
|
NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.
|
T6541 |
Ibutilide Fumarate
|
122647-32-9
|
99.68%
|
|
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
|
TN1721 |
Gypenoside L
|
94987-09-4
|
99.65%
|
|
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also i...
|
T16339 |
Norverapamil hydrochloride
|
67812-42-4
|
99.63%
|
|
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel...
|
T0916 |
Butamben
|
94-25-7
|
99.61%
|
|
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
|
TQ0033 |
Zegocractin
|
1713240-67-5
|
99.59%
|
|
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.
|
T7056 |
Dronedarone
|
141626-36-0
|
99.58%
|
|
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
|
T6227 |
Benidipine hydrochloride
|
91599-74-5
|
99.56%
|
|
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
|
T21454 |
Nicardipine
|
55985-32-5
|
99.56%
|
|
Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
|
T2782 |
Catharanthine
|
2468-21-5
|
99.55%
|
|
Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).
|
T16448 |
PD173212
|
217171-01-2
|
99.54%
|
|
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently ...
|
T3060 |
Fasudil hydrochloride
|
105628-07-7
|
99.54%
|
|
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
|
T1422 |
Nilvadipine
|
75530-68-6
|
99.53%
|
|
Nilvadipine (FK235), a calcium channel blocker (CCB), is utilized for treatment of hypertension.
|
T20656 |
Verapamil
|
52-53-9
|
99.53%
|
|
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies ab...
|
TP1559L |
Ziconotide Acetate (107452-89-1 free base)
|
914454-03-8
|
99.52%
|
|
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (10...
|
T16873 |
SERCA2a activator 1
|
2139330-34-8
|
99.52%
|
|
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the ...
|