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Calcium Channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0858 Flufenamic acid 530-78-9 99.71%
Flufenamic acid
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
T0343 Nimodipine 66085-59-4 99.71%
Nimodipine
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T41190 AY 77 1835734-92-3 99.7%
AY 77
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
T3904 Gomisin J 66280-25-9 99.69%
Gomisin J
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
T12204 NecroX-5 1383718-29-3 99.68%
NecroX-5
NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.
T6541 Ibutilide Fumarate 122647-32-9 99.68%
Ibutilide Fumarate
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
TN1721 Gypenoside L 94987-09-4 99.65%
Gypenoside L
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also i...
T16339 Norverapamil hydrochloride 67812-42-4 99.63%
Norverapamil hydrochloride
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel...
T0916 Butamben 94-25-7 99.61%
Butamben
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
TQ0033 Zegocractin 1713240-67-5 99.59%
Zegocractin
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.
T7056 Dronedarone 141626-36-0 99.58%
Dronedarone
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T6227 Benidipine hydrochloride 91599-74-5 99.56%
Benidipine hydrochloride
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
T21454 Nicardipine 55985-32-5 99.56%
Nicardipine
Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
T2782 Catharanthine 2468-21-5 99.55%
Catharanthine
Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).
T16448 PD173212 217171-01-2 99.54%
PD173212
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently ...
T3060 Fasudil hydrochloride 105628-07-7 99.54%
Fasudil hydrochloride
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T1422 Nilvadipine 75530-68-6 99.53%
Nilvadipine
Nilvadipine (FK235), a calcium channel blocker (CCB), is utilized for treatment of hypertension.
T20656 Verapamil 52-53-9 99.53%
Verapamil
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies ab...
TP1559L Ziconotide Acetate (107452-89-1 free base) 914454-03-8 99.52%
Ziconotide  Acetate (107452-89-1 free base)
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (10...
T16873 SERCA2a activator 1 2139330-34-8 99.52%
SERCA2a activator 1
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the ...
Flufenamic acid
T0858
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
Nimodipine
T0343
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
AY 77
T41190
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
Gomisin J
T3904
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
NecroX-5
T12204
NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.
Ibutilide Fumarate
T6541
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, ...
Gypenoside L
TN1721
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also i...
Norverapamil hydrochloride
T16339
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel...
Butamben
T0916
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
Zegocractin
TQ0033
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.
Dronedarone
T7056
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
Benidipine hydrochloride
T6227
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
Nicardipine
T21454
Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
Catharanthine
T2782
Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).
PD173212
T16448
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently ...
Fasudil hydrochloride
T3060
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
Nilvadipine
T1422
Nilvadipine (FK235), a calcium channel blocker (CCB), is utilized for treatment of hypertension.
Verapamil
T20656
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies ab...
Ziconotide Acetate (107452-89-1 free base)
TP1559L
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (10...
SERCA2a activator 1
T16873
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the ...
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TargetMol