T38808 |
Cyclamic acid sodium
|
139-05-9
|
99.84%
|
|
Cyclamic acid sodium (Cyclohexylsulfamicacidsodium) is a carbonic anhydrase inhibitor and one of the most widely used artificial sweeteners in food and pharmaceu...
|
T2616 |
PIK-93
|
593960-11-3
|
99.83%
|
|
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
|
T6503 |
Fluorometholone Acetate
|
3801-06-7
|
99.77%
|
|
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
|
T6S0221 |
Eriocitrin
|
13463-28-0
|
99.77%
|
|
1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress....
|
T0465 |
Ellagic acid
|
476-66-4
|
99.76%
|
|
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the ...
|
T1409 |
Methocarbamol
|
532-03-6
|
99.75%
|
|
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment...
|
T67774 |
Compound CDy9
|
952306-80-8
|
99.75%
|
|
Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
|
T34093 |
PNNP
|
330-13-2
|
99.73%
|
|
pNNP (Nitrophenylphosphate) can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori...
|
T25372 |
EMD57033
|
147527-31-9
|
99.72%
|
|
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
|
T2134 |
Dorzolamide hydrochloride
|
130693-82-2
|
99.48%
|
|
Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that ...
|
T1999 |
Taselisib
|
1282512-48-4
|
99.46%
|
|
Taselisib (GDC-0032) is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplasti...
|
T9323 |
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
|
654-62-6
|
99.34%
|
|
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-tumor...
|
T0114 |
Trichlormethiazide
|
133-67-5
|
99.32%
|
|
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
|
T2530 |
Levosimendan
|
141505-33-1
|
99.32%
|
|
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart...
|
T77631 |
Enpp/Carbonic anhydrase-IN-2
|
2883495-39-2
|
99.13%
|
|
Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.0...
|
T4321 |
Indisulam
|
165668-41-7
|
99.07%
|
|
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing...
|
T68136 |
(Iso)-Samixogrel
|
133276-52-5
|
98.67%
|
|
(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
|
T73177 |
HCAII-IN-9
|
2878477-18-8
|
98.63%
|
|
hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCA...
|
T2S0357 |
6-Hydroxycoumarin
|
6093-68-1
|
98.5%
|
|
6-Hydroxycoumarin (6-hydroxychromen-2-one) exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. ...
|
T21294 |
Polmacoxib
|
301692-76-2
|
98.49%
|
|
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and m...
|