Casein Kinase

The Casein kinase 1 family of protein kinases are serine/threonine-selective enzymes that function as regulators of signal transduction pathways in most eukaryotic cell types. CK1 isoforms are involved in Wnt signaling, circadian rhythms, nucleo-cytoplasmic shuttling of transcription factors, DNA repair, and DNA transcription.

Cat. No.	Product name	CAS No.	Purity
T73375	CK2-IN-4	313985-59-0	99.75%
T73375	CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM. CK2-IN-4 has potential anticancer ah and anti-inflammatory activity for the study of v...
T5358	Longdaysin	1353867-91-0	99.74%
T5358	Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 µM). It also can inhibit ERK2 (IC50: 52 µM).
T6150	TAK-715	303162-79-0	99.69%
T6150	TAK-715 is a p38 MAPK inhibitor for p38α.
T9356	(E/Z)-GO289	694522-87-7	99.68%
T9356	(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of canc...
T77709	Casein kinase 1δ-IN-8	851396-73-1	99.66%
T77709	Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.
T2048	LY-364947	396129-53-6	99.65%
T2048	LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
T7390	DMAT	749234-11-5	99.58%
T7390	DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
T15024	Silmitasertib sodium salt	1309357-15-0	99.49%
T15024	Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
T2259	Silmitasertib	1009820-21-6	99.47%
T2259	Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).
T60295	Casein kinase 1δ-IN-1	851871-94-8	99.46%
T60295	Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ. Casein kinase 1δ-IN-1 can be used in the study of neurodegene...
T2695	TBB	17374-26-4	99.45%
T2695	TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
T60067	WAY-297174	442571-27-9	99.43%
T60067	WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.
T3073	PF-670462	950912-80-8	99.42%
T3073	PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
T64350	Casein kinase 1δ-IN-3	349438-77-3	99.42%
T64350	Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.
T71339	BMS-863233 HCl	1169562-71-3	99.42%
T71339	BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215 and...
T16528	PI-828	942289-87-4	99.39%
T16528	PI-828 is a phosphatidylinositol 3-kinase (PI3K) inhibitor, which is widely used to study the physiological function of PI3K and also promotes stem cell differen...
T3352	XL413	1169558-38-6	99.38%
T3352	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the a...
T60608	FPFT-2216	2367619-87-0	99.35%
T60608	FPFT-2216 is a "molecular glue" compound that degrades IKZF6, IKZF1, DE1D, and CK3α. FPFT-2216 has potential antitumor activity and can be used to study immune s...
T21915	TBCA	934358-00-6	99.31%
T21915	TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 ove...
T6208	AS-252424	900515-16-4	99.26%
T6208	AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.