Caspase

Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation. They are named caspases due to their specific cysteine protease activity – a cysteine in its active site nucleophilically attacks and cleaves a target protein only after an aspartic acid residue.

Cat. No.	Product name	CAS No.	Purity
TN3614	Cearoin	52811-37-7	98%
TN3614	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
TN2895	3,5-Dicaffeoyl-epi-quinic acid	879305-14-3	98%
TN2895	3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases.
T13764	Lycopodine	466-61-5	98%
T13764	Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis...
TMA0153	Safflor Yellow A	85532-77-0	98%
TMA0153	Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis.
TN4107	Ganoderic acid X	86377-53-9	98%
TN4107	Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.
TN3681	Clerosterol	2364-23-0	98%
TN3681	Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cy...
TN3621	Centrolobol	30359-01-4	98%
TN3621	(-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. Centrolobol exhibits strong...
TN4903	Regiolone	137494-04-3	98%
TN4903	Regiolone demonstrates phytotoxicity. Regiolone also has anti-proliferative and apoptotic activities, it can induce apoptosis in MCF-7 cells through the caspase-...
T15180	Duocarmycin A	118292-34-5	98%
T15180	Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as ...
T4S2012	Dihydrosanguinarine	3606-45-9	99.99%
T4S2012	Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa,and has antifungal and anticancer activity.
T8652	CASP3 Activator 1541	1100353-03-4	99.98%
T8652	CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
T6191	Tasisulam	519055-62-0	99.97%
T6191	Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.
TN1854	Lasiodin	28957-08-6	99.90%
TN1854	Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor...
TN1807	Isoverticine	23496-43-7	99.88%
TN1807	Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.
T10990	Dehydrocorydaline chloride	10605-03-5	99.88%
T10990	Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
TN1677	Gartanin	33390-42-0	99.85%
TN1677	Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through ...
T4085	Paris saponin VII	68124-04-9	99.83%
T4085	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T7019	Z-IETD-FMK	210344-98-2	99.81%
T7019	Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.
T4S1335	Daphnoretin	2034-69-7	99.80%
T4S1335	1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, o...
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one	569-83-5	99.79%
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with...