Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor. |
Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by...
ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. |
||C3a 70-77 2TFA(63555-63-5(free base))
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a. |
Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. D...