Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX). |
Phenylmethanesulfonyl fluoride (PMSF) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex. |
Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction. |
Balicatib is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. |
||Calpain Inhibitor III
Calpain Inhibitor III is a Cysteine protease. |
PD 151746 is a selective, cell-permeable calpain inhibitor (Ki: 0.26/5.33 μM, μ-Calpain/m-calpain). |
N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies. |
||CA-074 methyl ester
CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects. |
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity. |
E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM. |
Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibit...
Calpeptin is a potent, cell-permeable calpain inhibitor. |
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent. |
Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. |
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases. |
P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM. |
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), inter...
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity. |
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM) |
LY 3000328 is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S). |
MIV-247 is a selective inhibitor of cathepsin S (human, mouse and cynomolgus monkey cathepsin S with Kis of 2.1, 4.2 and 7.5 nM , respectively). |
||Cysteine protease inhibitor-2
Cysteine protease inhibitor 2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor 2 inhibited DCT11...
S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 µM).It suppresses autophagy flux. |
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM). |
GLPG2451 effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.GLPG2451 is a cystic fibrosis transmembrane conductance regulat...
||Cathepsin Inhibitor 2
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor ,has a Ki of <20 nM. |
K777 is an orally active and irreversible cysteine protease inhibitor. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 is a...
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol is a β-adrenergic blocker. |
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibi...
ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM). |
ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334...
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases. |
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine prot...
LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo. LV-320 is a potent and uncompetitive AT...