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Search Results for " dna-rna-synthesis "

Targets

186

Compounds

58

Natural Products

2

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T12019 Methylproamine Others
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
T36757 DMT-dU-CE Phosphoramidite DNA/RNA Synthesis
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.
T6801 CeMMEC13 Carboxypeptidase , DNA/RNA Synthesis
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
T8873 Bractoppin Others , DNA/RNA Synthesis
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...
TP1115 L-Asparaginase L-​ASNase Others
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a...
T15611 JH-RE-06 DNA/RNA Synthesis
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...
T8354 Triazavirin Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T1154 Rifaximin DNA/RNA Synthesis , Antibacterial , Antibiotic
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting...
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
T36756 DMT-dG(ib) Phosphoramidite DNA/RNA Synthesis
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
T2100 CX-5461 DNA/RNA Synthesis
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.
T8955 PCNA-I1 Others
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.
T2037 TH588 DNA/RNA Synthesis , MTH1
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.
T8886 NITD-2 DNA/RNA Synthesis
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu...
T1349 5-Fluorouridine Others , DNA/RNA Synthesis
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...
T40168 DHODH-IN-16 Dehydrogenase
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
T2410 Nedaplatin NSC 375101D DNA/RNA Synthesis
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand...
T8747 Levofloxacin hydrochloride DNA gyrase , Topoisomerase
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh...
T36687 Ac-rC Phosphoramidite Nucleoside Antimetabolite/Analog
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
T4517 L189 DNA , DNA/RNA Synthesis
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
T0164 Oxaliplatin L-OHP DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...
T15235 Enocitabine Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ...
T8003 Methotrexate disodium Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
T7747 Datelliptium chloride hydrochloride DNA/RNA Synthesis
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
T14501 BAY-2402234 Dehydrogenase , DNA/RNA Synthesis
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.
T3279 Silver sulfadiazine Silvadene,Dermazin,Flamazine DNA/RNA Synthesis , Antibacterial , Antibiotic
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.
T16703 Quarfloxin CX-3543 DNA/RNA Synthesis
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...
T1233 Oxolinic acid Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
T15793 Lurbinectedin PM01183 Others
Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.
T8648 6-AZATHYMINE Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis , Antibacterial
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic...
T3103 L67 DNA Ligase Inhibitor DNA , DNA/RNA Synthesis
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T9103 BVDV-IN-1 DNA/RNA Synthesis
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to...
T40661 ML-60218 DNA/RNA Synthesis
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.
T11020 DHODH-IN-11 Dehydrogenase , DNA/RNA Synthesis
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
T4345 CeMMEC1 CeMMEC1 HCl Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
T5017 Nimustine Hydrochloride Nidran hydrochloride Apoptosis , Others , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.
T1058 Carboplatin NSC 241240,CBDCA,JM-8 DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
T26674 AT-130 AT 130 HBV , DNA/RNA Synthesis
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
T13166 TK216 Others , DNA/RNA Synthesis
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.
T12438 PfDHODH-IN-1 Dehydrogenase , Parasite
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
T9121 AG-636 Dehydrogenase , DNA/RNA Synthesis
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
T13659 DMTr-LNA-5MeU-3-CED-phosphoramidite Nucleoside Antimetabolite/Analog
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
T2069L TH287 hydrochloride DNA/RNA Synthesis , MTH1
TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
T11546 HDHODH-IN-1 Dehydrogenase
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.
T0220 Foscarnet sodium Phosphonoformate Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T6357 (S)-crizotinib ent-crizotinib Apoptosis , DNA/RNA Synthesis , MTH1
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
T21463 Temozolomide Acid TMZA Others
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt...
T3489 Dasabuvir ABT-333 HCV Protease
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra...
T4356 POL1-IN-1 Compound 3A DNA/RNA Synthesis
POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
T12718L RG7800 RO6885247 Others , DNA/RNA Synthesis
RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.

Compounds

Methylproamine
T12019
Synonym:
Target: Others
DMT-dU-CE Phosphoramidite
T36757
Synonym:
Target: DNA/RNA Synthesis
CeMMEC13
T6801
Synonym:
Target: Carboxypeptidase, DNA/RNA Synthesis
Bractoppin
T8873
Synonym:
Target: Others, DNA/RNA Synthesis
L-Asparaginase
TP1115
Synonym: L-​ASNase
Target: Others
JH-RE-06
T15611
Synonym:
Target: DNA/RNA Synthesis
Triazavirin
T8354
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis
Rifaximin
T1154
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
BMH-21
T1767
Synonym: BMH21
Target: DNA/RNA Synthesis
DMT-dG(ib) Phosphoramidite
T36756
Synonym:
Target: DNA/RNA Synthesis
CX-5461
T2100
Synonym:
Target: DNA/RNA Synthesis
PCNA-I1
T8955
Synonym:
Target: Others
TH588
T2037
Synonym:
Target: DNA/RNA Synthesis, MTH1
NITD-2
T8886
Synonym:
Target: DNA/RNA Synthesis
5-Fluorouridine
T1349
Synonym:
Target: Others, DNA/RNA Synthesis
DHODH-IN-16
T40168
Synonym:
Target: Dehydrogenase
Nedaplatin
T2410
Synonym: NSC 375101D
Target: DNA/RNA Synthesis
Levofloxacin hydrochloride
T8747
Synonym:
Target: DNA gyrase, Topoisomerase
Ac-rC Phosphoramidite
T36687
Synonym:
Target: Nucleoside Antimetabolite/Analog
L189
T4517
Synonym:
Target: DNA, DNA/RNA Synthesis
Oxaliplatin
T0164
Synonym: L-OHP
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
Enocitabine
T15235
Synonym:
Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis
Methotrexate disodium
T8003
Synonym:
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate
Datelliptium chloride hydrochloride
T7747
Synonym:
Target: DNA/RNA Synthesis
BAY-2402234
T14501
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
Silver sulfadiazine
T3279
Synonym: Silvadene,Dermazin,Flamazine
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Quarfloxin
T16703
Synonym: CX-3543
Target: DNA/RNA Synthesis
Oxolinic acid
T1233
Synonym: Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox
Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic
Lurbinectedin
T15793
Synonym: PM01183
Target: Others
6-AZATHYMINE
T8648
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial
L67
T3103
Synonym: DNA Ligase Inhibitor
Target: DNA, DNA/RNA Synthesis
BVDV-IN-1
T9103
Synonym:
Target: DNA/RNA Synthesis
ML-60218
T40661
Synonym:
Target: DNA/RNA Synthesis
DHODH-IN-11
T11020
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
CeMMEC1
T4345
Synonym: CeMMEC1 HCl
Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis
Nimustine Hydrochloride
T5017
Synonym: Nidran hydrochloride
Target: Apoptosis, Others, DNA Alkylator/Crosslinker, DNA/RNA Synthesis
Carboplatin
T1058
Synonym: NSC 241240,CBDCA,JM-8
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
AT-130
T26674
Synonym: AT 130
Target: HBV, DNA/RNA Synthesis
TK216
T13166
Synonym:
Target: Others, DNA/RNA Synthesis
PfDHODH-IN-1
T12438
Synonym:
Target: Dehydrogenase, Parasite
AG-636
T9121
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
DMTr-LNA-5MeU-3-CED-phosphoramidite
T13659
Synonym:
Target: Nucleoside Antimetabolite/Analog
TH287 hydrochloride
T2069L
Synonym:
Target: DNA/RNA Synthesis, MTH1
hDHODH-IN-1
T11546
Synonym:
Target: Dehydrogenase
Foscarnet sodium
T0220
Synonym: Phosphonoformate
Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis
(S)-crizotinib
T6357
Synonym: ent-crizotinib
Target: Apoptosis, DNA/RNA Synthesis, MTH1
Temozolomide Acid
T21463
Synonym: TMZA
Target: Others
Dasabuvir
T3489
Synonym: ABT-333
Target: HCV Protease
POL1-IN-1
T4356
Synonym: Compound 3A
Target: DNA/RNA Synthesis
RG7800
T12718L
Synonym: RO6885247
Target: Others, DNA/RNA Synthesis
1 2 3 4
Cat No. Product Name Synonyms Targets
T13969 Xanthopterin (hydrate) Others , DNA/RNA Synthesis
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.
T21498 Phleomycin DNA/RNA Synthesis , Antibacterial , Antibiotic
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
T40179 Sodium Camptothecin DNA/RNA Synthesis
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...
T7520 Deoxycytidine triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T2S1635 3-Isomangostin MTH1
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...
T37101 1-Hydroxyanthraquinone DNA/RNA Synthesis
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
T5901 3-Hydroxy-2-methylpyridine Others
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
T1068 Dithranol 1,8,9-trihydroxyanthracene,cignoline,Anthralin Others , DNA/RNA Synthesis
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T6S0139 Neobavaisoflavone Apoptosis , DNA/RNA Synthesis
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...
T35455 N-Nitrosodiethylamine Diethylnitrosamine,NDEA DNA/RNA Synthesis
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...
TQ0184 Chebulinic acid ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T6S0232 Eriodictyol Huazhongilexone Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3....
TN2132 Quinizarin 1,4-Dihydroxyanthraquinone Others , DNA/RNA Synthesis , Antifungal
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product
T16674 Pseudouridine Endogenous Metabolite
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
T0064 Adenine Vitamin B4,6-Aminopurine DNA/RNA Synthesis , Endogenous Metabolite , AChR
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic...
TWP2911 Thymidine 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin Others , DNA/RNA Synthesis , Endogenous Metabolite
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
T4593 ISOPIMPINELLIN 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen Antiviral , DNA/RNA Synthesis , Parasite
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T2998 Dihydromyricetin Ampelopsin,Ampeloptin Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy...
T13791 N2-methylguanine N2-methylguanine DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.
T6567 Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin Topoisomerase , Antibacterial , Antibiotic
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
T7004 Tubercidin Sparsomycin A,7-Deazaadenosine Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
T6116 Bleomycin Sulfate Blenoxane,NSC125066 DNA/RNA Synthesis , Antibiotic
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
T6758 Anisomycin Flagecidin,NSC 76712,Wuningmeisu C Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
TN1097 β-Boswellic acid Beta-boswellic acid Lipoxygenase , DNA/RNA Synthesis
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.
T6225 Adenine hydrochloride Adenine HCl,6-Aminopurine hydrochloride DNA/RNA Synthesis , Endogenous Metabolite
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
T20945 2,4-D Hedonal,Macondray,2,4-D acid,Chloroxone DNA/RNA Synthesis
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti...
T3343 5-methoxyflavone 5-methoxy-2-phenylchromen-4-one DNA/RNA Synthesis
5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
T7174 Urolithin A Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
T6369 Adenine hemisulfate Diadenine sulphate,Adenine sulfate,Adeninsulfat DNA/RNA Synthesis , Endogenous Metabolite
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
T1507 Streptozocin STZ,Streptozotocin,NSC-85998,U 9889 DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th...
T0974 Novobiocin Sodium Albamycinsodium,Cathomycin,Albamycin Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T38427 DUTP trisodium 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate DNA/RNA Synthesis
dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
T0062 Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin DNA/RNA Synthesis , Endogenous Metabolite
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.
T40426 Cytidine 5'-diphosphate trisodium salt CDP Others
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp...
T6194 Fidaxomicin Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...
T1272 Cytarabine Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T4706 Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction...
T2A2537 Guanine Pearl essence,Mearlmaid,2-Aminohypoxanthine Others , DNA/RNA Synthesis , Endogenous Metabolite
Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids.
T9086 Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt DNA/RNA Synthesis
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ...
T3376 Cynaroside Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside Others , Influenza Virus , DNA/RNA Synthesis
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
T1511 Daunorubicin hydrochloride Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T1703 SN-38 NK012,SN 38 DNA/RNA Synthesis , Topoisomerase , Autophagy
SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 has antitumor activity and induces autophagy.
T33817 Orellanine 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one Others
Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat l...
T7937 2-Amino-4'-fluorobenzophenone Others
2-Amino-4'-fluorobenzophenone is a derivative of benzophenone. It is used in the synthesis of p-fluorobenzoyl chloride and has also been used as a fluorescent probe for biochemical studies such as DNA and RNA detection.
TN1258 3-Acetyl-beta-boswellic acid 3-O-Acetyl-beta-boswellic acid DNA/RNA Synthesis
3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM.
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Natural Products

Xanthopterin (hydrate)
T13969
Synonym:
Target: Others, DNA/RNA Synthesis
Phleomycin
T21498
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Sodium Camptothecin
T40179
Synonym:
Target: DNA/RNA Synthesis
Deoxycytidine triphosphate
T7520
Synonym:
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite
3-Isomangostin
T2S1635
Synonym:
Target: MTH1
1-Hydroxyanthraquinone
T37101
Synonym:
Target: DNA/RNA Synthesis
3-Hydroxy-2-methylpyridine
T5901
Synonym:
Target: Others
5-Methylcytosine
T5270
Synonym:
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
Dithranol
T1068
Synonym: 1,8,9-trihydroxyanthracene,cignoline,Anthralin
Target: Others, DNA/RNA Synthesis
Euscaphic acid
TN1134
Synonym:
Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor
Neobavaisoflavone
T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
N-Nitrosodiethylamine
T35455
Synonym: Diethylnitrosamine,NDEA
Target: DNA/RNA Synthesis
Chebulinic acid
TQ0184
Synonym:
Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad
Eriodictyol
T6S0232
Synonym: Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
Quinizarin
TN2132
Synonym: 1,4-Dihydroxyanthraquinone
Target: Others, DNA/RNA Synthesis, Antifungal
Pseudouridine
T16674
Synonym:
Target: Endogenous Metabolite
Adenine
T0064
Synonym: Vitamin B4,6-Aminopurine
Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR
Thymidine
TWP2911
Synonym: 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
ISOPIMPINELLIN
T4593
Synonym: 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen
Target: Antiviral, DNA/RNA Synthesis, Parasite
Aplidine
T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
Dihydromyricetin
T2998
Synonym: Ampelopsin,Ampeloptin
Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy
N2-methylguanine
T13791
Synonym: N2-methylguanine
Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial
Levofloxacin
T6567
Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin
Target: Topoisomerase, Antibacterial, Antibiotic
Tubercidin
T7004
Synonym: Sparsomycin A,7-Deazaadenosine
Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic
Bleomycin Sulfate
T6116
Synonym: Blenoxane,NSC125066
Target: DNA/RNA Synthesis, Antibiotic
Anisomycin
T6758
Synonym: Flagecidin,NSC 76712,Wuningmeisu C
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK
β-Boswellic acid
TN1097
Synonym: Beta-boswellic acid
Target: Lipoxygenase, DNA/RNA Synthesis
Adenine hydrochloride
T6225
Synonym: Adenine HCl,6-Aminopurine hydrochloride
Target: DNA/RNA Synthesis, Endogenous Metabolite
2,4-D
T20945
Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone
Target: DNA/RNA Synthesis
5-methoxyflavone
T3343
Synonym: 5-methoxy-2-phenylchromen-4-one
Target: DNA/RNA Synthesis
Urolithin A
T7174
Synonym:
Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite
Adenine hemisulfate
T6369
Synonym: Diadenine sulphate,Adenine sulfate,Adeninsulfat
Target: DNA/RNA Synthesis, Endogenous Metabolite
Streptozocin
T1507
Synonym: STZ,Streptozotocin,NSC-85998,U 9889
Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy
Novobiocin Sodium
T0974
Synonym: Albamycinsodium,Cathomycin,Albamycin
Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy
dUTP trisodium
T38427
Synonym: 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate
Target: DNA/RNA Synthesis
Folic acid
T0062
Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin
Target: DNA/RNA Synthesis, Endogenous Metabolite
Cytidine 5'-diphosphate trisodium salt
T40426
Synonym: CDP
Target: Others
Fidaxomicin
T6194
Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic
Cytarabine
T1272
Synonym: Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Uridine-5'-diphosphate disodium salt
T4706
Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd
Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor
Guanine
T2A2537
Synonym: Pearl essence,Mearlmaid,2-Aminohypoxanthine
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
Deoxythymidine-5'-triphosphate trisodium
T9086
Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt
Target: DNA/RNA Synthesis
Cynaroside
T3376
Synonym: Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside
Target: Others, Influenza Virus, DNA/RNA Synthesis
Daunorubicin hydrochloride
T1511
Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin
Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
SN-38
T1703
Synonym: NK012,SN 38
Target: DNA/RNA Synthesis, Topoisomerase, Autophagy
Orellanine
T33817
Synonym: 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
Target: Others
2-Amino-4'-fluorobenzophenone
T7937
Synonym:
Target: Others
3-Acetyl-beta-boswellic acid
TN1258
Synonym: 3-O-Acetyl-beta-boswellic acid
Target: DNA/RNA Synthesis

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02402 WTAP Protein, Human, Recombinant (GST) Human E. coli
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif...
TMPH-01522 HIV-2 (subtype A, isolate ROD) Protein Vpx (His) HIV-2 Yeast
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the...
Cat No. Product Name
L5500 Toxic Compound Library

277 compounds
A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);
L8100 Cell Cycle Compound Library

695 compounds
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
TargetMol