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DNA gyrase

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known as topoisomerases that are involved in the control of topological transitions of DNA.

Cat No.	product name
T0116	Balofloxacin	Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.
T0250	Ciprofloxacin hydrochloride	Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline.
T0717	Enoxacin Sesquihydrate	Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T0974	Novobiocin Sodium	Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces nive...
T1095	Sparfloxacin	Sparfloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
T1294	Fleroxacin	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
T1306	Norfloxacin	Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
T1451	Levofloxacin Hemihydrate	Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxac...
T1492	Gemifloxacin mesylate	Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin M...
T2353	BRD7716	BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
TQ0063	Zoliflodacin	Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-posi...
T7786	Tryptanthrin	Tryptanthrin is a natural DNA gyrase inhibitor.
T13231	Trovafloxacin	Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.
T8747	Levofloxacin hydrochloride	Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxa...