T11056 |
DLK-IN-1
|
1620574-24-4
|
98%
|
|
DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, re...
|
T11440 |
GNE-8505
|
1620573-48-9
|
98%
|
|
GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).
|
T12813L |
Seco-Duocarmycin SA
|
144667-38-9
|
98%
|
|
Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
|
T19300 |
Duocarmycin Analog
|
372954-15-9
|
98%
|
|
Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.
|
T3091 |
Carmustine
|
154-93-8
|
99.97%
|
|
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.
|
T1601 |
Lomustine
|
13010-47-4
|
99.86%
|
|
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
|
T0923 |
Busulfan
|
55-98-1
|
99.77%
|
|
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully...
|
T6798 |
Tretazicar
|
21919-05-1
|
99.7%
|
|
CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and ...
|
T2495 |
Lomeguatrib
|
192441-08-0
|
99.62%
|
|
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
|
T21297 |
Miriplatin hydrate
|
250159-48-9
|
99.6%
|
|
Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Mi...
|
T0975 |
Chlorambucil
|
305-03-3
|
99.58%
|
|
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cyc...
|
T17159 |
Treosulfan
|
299-75-2
|
99.26%
|
|
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T11120 |
Duocarmycin TM
|
157922-77-5
|
99.15%
|
|
Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
|
T3707 |
GNE-3511
|
1496581-76-0
|
98.64%
|
|
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
|
T26978 |
CEP-40125
|
1456608-94-8
|
98.05%
|
|
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.
|
T15771 |
Lobaplatin
|
135558-11-1
|
98.00%
|
|
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent w...
|
T7539 |
O6-Benzylguanine
|
19916-73-5
|
98%
|
|
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical acti...
|
T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The...
|