T6894 |
ML264
|
1550008-55-3
|
98.72%
|
|
ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.
|
T7004 |
Tubercidin
|
69-33-0
|
98.66%
|
|
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA repli...
|
T26674 |
AT-130
|
211364-06-6
|
98.62%
|
|
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level ...
|
TNU0436 |
2-Thiocytidine
|
13239-97-9
|
98.59%
|
|
2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocyt...
|
T1307 |
Carmofur
|
61422-45-5
|
98.59%
|
|
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencep...
|
T4060 |
Acelarin
|
840506-29-8
|
98.56%
|
|
Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
|
TN1237 |
3-O-Methylgallic acid
|
3934-84-7
|
98.53%
|
|
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may...
|
T0220 |
Foscarnet sodium
|
63585-09-1
|
98.52%
|
|
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesv...
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
98.5%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
T2516 |
Amuvatinib
|
850879-09-3
|
98.48%
|
|
Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
|
T13166 |
TK216
|
1903783-48-1
|
98.45%
|
|
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.
|
TQ0184 |
Chebulinic acid
|
18942-26-2
|
98.4%
|
|
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
|
T5363 |
Tempo
|
2564-83-2
|
98.35%
|
|
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a stru...
|
T60187 |
RP-6685
|
2832047-80-8
|
98.34%
|
|
RP-6685, a highly potent and selective inhibitor of DNA polymerase theta (Polθ), manifests remarkable oral activity. With an IC 50 value of 5.8 nM in the PicoGre...
|
T1465 |
Mupirocin
|
12650-69-0
|
98.33%
|
|
Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.
|
T9168 |
NSC 617145
|
203115-63-3
|
98.31%
|
|
NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manne...
|
TN1097 |
β-Boswellic acid
|
631-69-6
|
98.31%
|
|
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic acti...
|
T25466 |
GS-9191
|
859209-84-0
|
98.28%
|
|
GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetr...
|
T8842 |
IMT1B
|
2304621-06-3
|
98.26%
|
|
IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of the mitochondrial RNA polymerase (POLRMT), effectively suppressing m...
|
T12935 |
SMN-C3
|
1449597-34-5
|
98.21%
|
|
SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).
|