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Search Result

Search Results for " dehydrogenase inhibitor "

Targets

Dehydrogenase

255

Compounds

32

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T15435 GSK2837808A Dehydrogenase
GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
T39280 Nitrofen Others
Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.
T11546 HDHODH-IN-1 Dehydrogenase
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.
T16161 Mutant IDH1 inhibitor Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
T11829 LDH-IN-1 Dehydrogenase
LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
T7741 DS-1001b Dehydrogenase , Isocitrate Dehydrogenase (IDH)
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
T7835 CM10 CM 10 Dehydrogenase
CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.
T12196 NCT-505 Dehydrogenase
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 μM, 22.8 μM, 20.1 μM, >57 μM respectively...
T15550 IDH-305 Dehydrogenase
IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor. IDH-305 shows greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50s: 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 µM (...
T6903 NCT-501 NCT501 Dehydrogenase
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.
TQ0042 BAY-1436032 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).
T15827 LY 345899 DHFR
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
T15551 IDH889 Dehydrogenase
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt).
T2346 Enasidenib AG-221 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity.
T9394 CHIKV-IN-2 Dehydrogenase
CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec...
T1809 AGI-6780 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
T40168 DHODH-IN-16 Dehydrogenase
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
T2662 Alda-1 Alda 1 Apoptosis , Dehydrogenase
Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH2*1 and the Asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).
T11765 KPLH1130 Dehydrogenase , PDK
KPLH1130, a specific pyruvate dehydrogenase kinase (PDK) inhibitor, enhances glucose tolerance in mice fed a high-fat diet (HFD). It effectively hinders macrophage polarization and mitigates proinflammatory reactions.
T17224 VER-246608 Dehydrogenase , PDK
VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively).VER-246608 disrupts Warburg metabolism an...
T10140 4-Diethylaminobenzaldehyde Dehydrogenase
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μM).
T22336 Galloflavin Dehydrogenase
Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.
T14501 BAY-2402234 Dehydrogenase , DNA/RNA Synthesis
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.
T23533 WIN 18446 Dehydrogenase
inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
T2447 AZD7545 Dehydrogenase
AZD7545 is a potent PDHK inhibitor.
T22350 JX06 Apoptosis , Dehydrogenase , PDK
JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.
T4295 (R)-GNE-140 GNE-140 Dehydrogenase
(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.
T9121 AG-636 Dehydrogenase , DNA/RNA Synthesis
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
T8767 PfDHODH-IN-2 Dehydrogenase , Parasite
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of m...
T16384 Olutasidenib FT-2102 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Iso...
T12128 Mutant IDH1-IN-2 Isocitrate Dehydrogenase (IDH)
Mutant IDH1-IN-2 is a mutant Isocitrate dehydrogenase (IDH) proteins inhibitor
T11020 DHODH-IN-11 Dehydrogenase , DNA/RNA Synthesis
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
T12438 PfDHODH-IN-1 Dehydrogenase , Parasite
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
T38163 ML-148 Dehydrogenase
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostagla...
T2104 AGI-5198 IDH-C35 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).
T13774 ML390 Others , Dehydrogenase
ML390 exerts its potent differentiation effect on multiple leukemia models.
T2121 SW033291 Dehydrogenase
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
T3617 Ivosidenib AG-120 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhi...
T3175 LDHA-IN-4 AZ 33,AZ-33,LDHA Inhibitor,AZ33 Dehydrogenase
LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.
T2601 Vidofludimus SC12267,4sc-101 Dehydrogenase , DNA/RNA Synthesis , Interleukin
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T1818 Tenovin-6 Tenovin 6 Dehydrogenase , Sirtuin , Autophagy
Tenovin-6 is a p53 transcriptional activity agonist.
T1919 Tenovin-1 Tenovin 1 Mdm2 , Dehydrogenase , Sirtuin , p53 , Autophagy
Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.
T7307 Vorasidenib PVM/MA,AG-881 Isocitrate Dehydrogenase (IDH)
Vorasidenib (PVM/MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
T8480 Tenovin-6 Hydrochloride Dehydrogenase , Sirtuin , HDAC , p53 , Autophagy
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .
T2043 Mutant IDH1-IN-1 IDH1-IN-1 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.
T0054 Disulfiram Tetraethylthiuram disulfide,NSC 190940,TETD Dehydrogenase , Interleukin , Pyroptosis
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutely sensitized to alcohol and also inhibits GSDMD pore format...
T5325 Nifurtimox BAY-2502,BAY-A-2502 Dehydrogenase , Parasite
Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi- epimastigotes, respectively).
T0765 Fomepizole Antizol-Vet,4-Methylpyrazole,Antizol P450 , CAT , AChR
Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata...
T12412L PDK4-IN-1 hydrochloride Apoptosis , PDK
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM)
T10384 Farudodstat ASLAN003 Apoptosis , Dehydrogenase , DNA/RNA Synthesis
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.

Compounds

GSK2837808A
T15435
Synonym:
Target: Dehydrogenase
Nitrofen
T39280
Synonym:
Target: Others
hDHODH-IN-1
T11546
Synonym:
Target: Dehydrogenase
Mutant IDH1 inhibitor
T16161
Synonym:
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
LDH-IN-1
T11829
Synonym:
Target: Dehydrogenase
DS-1001b
T7741
Synonym:
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
CM10
T7835
Synonym: CM 10
Target: Dehydrogenase
NCT-505
T12196
Synonym:
Target: Dehydrogenase
IDH-305
T15550
Synonym:
Target: Dehydrogenase
NCT-501
T6903
Synonym: NCT501
Target: Dehydrogenase
BAY-1436032
TQ0042
Synonym:
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
LY 345899
T15827
Synonym:
Target: DHFR
IDH889
T15551
Synonym:
Target: Dehydrogenase
Enasidenib
T2346
Synonym: AG-221
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
CHIKV-IN-2
T9394
Synonym:
Target: Dehydrogenase
AGI-6780
T1809
Synonym:
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
DHODH-IN-16
T40168
Synonym:
Target: Dehydrogenase
Alda-1
T2662
Synonym: Alda 1
Target: Apoptosis, Dehydrogenase
KPLH1130
T11765
Synonym:
Target: Dehydrogenase, PDK
VER-246608
T17224
Synonym:
Target: Dehydrogenase, PDK
4-Diethylaminobenzaldehyde
T10140
Synonym:
Target: Dehydrogenase
Galloflavin
T22336
Synonym:
Target: Dehydrogenase
BAY-2402234
T14501
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
WIN 18446
T23533
Synonym:
Target: Dehydrogenase
AZD7545
T2447
Synonym:
Target: Dehydrogenase
JX06
T22350
Synonym:
Target: Apoptosis, Dehydrogenase, PDK
(R)-GNE-140
T4295
Synonym: GNE-140
Target: Dehydrogenase
AG-636
T9121
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
PfDHODH-IN-2
T8767
Synonym:
Target: Dehydrogenase, Parasite
Olutasidenib
T16384
Synonym: FT-2102
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
Mutant IDH1-IN-2
T12128
Synonym:
Target: Isocitrate Dehydrogenase (IDH)
DHODH-IN-11
T11020
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
PfDHODH-IN-1
T12438
Synonym:
Target: Dehydrogenase, Parasite
ML-148
T38163
Synonym:
Target: Dehydrogenase
AGI-5198
T2104
Synonym: IDH-C35
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
ML390
T13774
Synonym:
Target: Others, Dehydrogenase
SW033291
T2121
Synonym:
Target: Dehydrogenase
Ivosidenib
T3617
Synonym: AG-120
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
LDHA-IN-4
T3175
Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33
Target: Dehydrogenase
Vidofludimus
T2601
Synonym: SC12267,4sc-101
Target: Dehydrogenase, DNA/RNA Synthesis, Interleukin
Tenovin-6
T1818
Synonym: Tenovin 6
Target: Dehydrogenase, Sirtuin, Autophagy
Tenovin-1
T1919
Synonym: Tenovin 1
Target: Mdm2, Dehydrogenase, Sirtuin, p53, Autophagy
Vorasidenib
T7307
Synonym: PVM/MA,AG-881
Target: Isocitrate Dehydrogenase (IDH)
Tenovin-6 Hydrochloride
T8480
Synonym:
Target: Dehydrogenase, Sirtuin, HDAC, p53, Autophagy
Mutant IDH1-IN-1
T2043
Synonym: IDH1-IN-1
Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)
Disulfiram
T0054
Synonym: Tetraethylthiuram disulfide,NSC 190940,TETD
Target: Dehydrogenase, Interleukin, Pyroptosis
Nifurtimox
T5325
Synonym: BAY-2502,BAY-A-2502
Target: Dehydrogenase, Parasite
Fomepizole
T0765
Synonym: Antizol-Vet,4-Methylpyrazole,Antizol
Target: P450, CAT, AChR
PDK4-IN-1 hydrochloride
T12412L
Synonym:
Target: Apoptosis, PDK
Farudodstat
T10384
Synonym: ASLAN003
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T4778 3-Hydroxybenzaldehyde Others , Dehydrogenase
3-Hydroxybenzaldehyde is a compound useful in organic synthesis.
T5705 Glomeratose A Dehydrogenase
Glomeratose A is a lactate dehydrogenase inhibitor.
TJS1382 Taraxerone Dehydrogenase
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dep...
T0809 Dicoumarol Dicumarol Dehydrogenase , NADPH , PDK
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; t...
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T4886 Dihydrouracil 5,6-Dihydrouracil Endogenous Metabolite
5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.
T3604 Sodium dichloroacetate Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...
T7964 Isomalt Palatinitol,Palatinit Others , Dehydrogenase
Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside
T10148 4-Hydroxynonenal 4-HNE Dehydrogenase , Endogenous Metabolite
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
T5S0620 3-Dehydrotrametenolic acid Dehydrotrametenolic acid Apoptosis , Others , Dehydrogenase
1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug.
T1335 Mycophenolic acid Mycophenolate,RS-61443 Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
T2207 Adrenosterone 11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G Androgen Receptor , Endogenous Metabolite
Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.
T5695 Dimethyl malonate Others
Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.
T10943 D-(-)-Lactic acid (R)-2-Hydroxypropionic acid Others , Endogenous Metabolite
D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydrogenase) in plants.
T3009 3-Nitropropanoic acid 3-NP acid,Bovinocidin,3-NP,β-Nitropropionic acid Apoptosis , Dehydrogenase , Antibacterial
3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.
T2S2211 Tenuifoliside C Dehydrogenase
Tenuifoliside C, isolated from polygala tenuifolia willd, is a target lactate dehydrogenase inhibitor. It significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1[1].
TN1829 Kakkalide Dehydrogenase
Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects.
T5S2195 Sibiricose A5 Dehydrogenase
Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.
T6293 Mycophenolate Mofetil TM-MMF,RS 61443 Apoptosis , Dehydrogenase , Drug Metabolite
Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
T17048 Tetradecanoylcarnitine L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine Endogenous Metabolite
Tetradecanoylcarnitine (L-Myristoylcarnitine) is an acylcarnitine involved in the beta-oxidation of long-chain fatty acids, and is a potential marker for very-long-chain coenzyme A dehydrogenase deficiency. alpha-Dihydro...
T6518 Gossypol Pogosin,BL 193,NSC 56817 BCL , Dehydrogenase
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
TN1182 11-​Keto-​beta-​boswellic acid 11-Keto-beta-boswellic acid Leukotriene Receptor , NF-κB , Lipoxygenase
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenas...
T5702 Tenuifoliside B Dehydrogenase
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...
TJS0341 7-Amino-4-(trifluoromethyl)coumarin Coumarin 151,AFC 5-HT Receptor
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluorometh...
T3019 Physcion Physcione,Parietin,Rheochrysidin Dehydrogenase , Antibacterial
Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM...
T5291 Malonic acid Carboxyacetic Acid,1,3-Propanedioic Acid,Propanedioic Acid Others
Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associa...
T14001 11-Beta-hydroxyandrostenedione NSC-17102,4-Androsten-11β-ol-3,17-dione Endogenous Metabolite
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme...
T4858 4-​Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid Endogenous Metabolite
4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydro...
TN4578 Monomethyl kolavate Antifection
Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM.
T15638 K-252c PKC
K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in ...
T60859 5-Pentadecylresorcinol
5-Pentadecylresorcinol (Adipostatin A) has good larvicidal activity against Aedes aegypti that is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH) with an IC 50 of 4.1 μM [1] [2].
T83133 Alternaphenol B2 Isocitrate Dehydrogenase (IDH)
Alternaphenol B2, a selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1m), is sourced from the coral-derived fungus Parengyodontium album SCSIO SX7W11. It exhibits inhibitory activity specifically against the ...

Natural Products

3-Hydroxybenzaldehyde
T4778
Synonym:
Target: Others, Dehydrogenase
Glomeratose A
T5705
Synonym:
Target: Dehydrogenase
Taraxerone
TJS1382
Synonym:
Target: Dehydrogenase
Dicoumarol
T0809
Synonym: Dicumarol
Target: Dehydrogenase, NADPH, PDK
Prunetin
T4S0878
Synonym: Prunusetin
Target: ERK, Dehydrogenase, NF-κB
Dihydrouracil
T4886
Synonym: 5,6-Dihydrouracil
Target: Endogenous Metabolite
Sodium dichloroacetate
T3604
Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)
Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK
Isomalt
T7964
Synonym: Palatinitol,Palatinit
Target: Others, Dehydrogenase
4-Hydroxynonenal
T10148
Synonym: 4-HNE
Target: Dehydrogenase, Endogenous Metabolite
3-Dehydrotrametenolic acid
T5S0620
Synonym: Dehydrotrametenolic acid
Target: Apoptosis, Others, Dehydrogenase
Mycophenolic acid
T1335
Synonym: Mycophenolate,RS-61443
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal
Adrenosterone
T2207
Synonym: 11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G
Target: Androgen Receptor, Endogenous Metabolite
Dimethyl malonate
T5695
Synonym:
Target: Others
D-(-)-Lactic acid
T10943
Synonym: (R)-2-Hydroxypropionic acid
Target: Others, Endogenous Metabolite
3-Nitropropanoic acid
T3009
Synonym: 3-NP acid,Bovinocidin,3-NP,β-Nitropropionic acid
Target: Apoptosis, Dehydrogenase, Antibacterial
Tenuifoliside C
T2S2211
Synonym:
Target: Dehydrogenase
Kakkalide
TN1829
Synonym:
Target: Dehydrogenase
Sibiricose A5
T5S2195
Synonym:
Target: Dehydrogenase
Mycophenolate Mofetil
T6293
Synonym: TM-MMF,RS 61443
Target: Apoptosis, Dehydrogenase, Drug Metabolite
Tetradecanoylcarnitine
T17048
Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine
Target: Endogenous Metabolite
Gossypol
T6518
Synonym: Pogosin,BL 193,NSC 56817
Target: BCL, Dehydrogenase
11-​Keto-​beta-​boswellic acid
TN1182
Synonym: 11-Keto-beta-boswellic acid
Target: Leukotriene Receptor, NF-κB, Lipoxygenase
Tenuifoliside B
T5702
Synonym:
Target: Dehydrogenase
7-Amino-4-(trifluoromethyl)coumarin
TJS0341
Synonym: Coumarin 151,AFC
Target: 5-HT Receptor
Physcion
T3019
Synonym: Physcione,Parietin,Rheochrysidin
Target: Dehydrogenase, Antibacterial
Malonic acid
T5291
Synonym: Carboxyacetic Acid,1,3-Propanedioic Acid,Propanedioic Acid
Target: Others
11-Beta-hydroxyandrostenedione
T14001
Synonym: NSC-17102,4-Androsten-11β-ol-3,17-dione
Target: Endogenous Metabolite
4-​Hydroxyphenylpyruvic acid
T4858
Synonym: 4-Hydroxyphenylpyruvic acid
Target: Endogenous Metabolite
Monomethyl kolavate
TN4578
Synonym:
Target: Antifection
K-252c
T15638
Synonym:
Target: PKC
5-Pentadecylresorcinol
T60859
Synonym:
Target:
Alternaphenol B2
T83133
Synonym:
Target: Isocitrate Dehydrogenase (IDH)

Recombinant Proteins

Species：
Human (1)
Mouse (1)
Expression System：
E. coli (2)
Tag：
His (2)
Cat No. Product Name Species Expression System
TMPY-00506 GAPDH Protein, Mouse, Recombinant (His) Mouse E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
TMPY-02446 GAPDH Protein, Human, Recombinant (His) Human E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
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