Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T0414	D-Mannitol	69-65-8	99.34%
T0414	D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the bod...
T11028	HDHODH-IN-4	1644156-56-8	99.31%
T11028	hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits mea...
T9859	SW209049	1673558-59-2	99.31%
T9859	SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.
T28424	PKUMDL-WQ-2101	304481-72-9	99.28%
T28424	PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.
T1491	Atovaquone	95233-18-4	99.28%
T1491	Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
T16277	NCT-502	1542213-00-2	99.25%
T16277	NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytoto...
T6157	Devimistat	95809-78-2	99.24%
T6157	Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, ...
T0972	Isoniazid	54-85-3	99.21%
T0972	Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic.
T5013	Brequinar	96187-53-0	99.21%
T5013	Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
T3617	Ivosidenib	1448347-49-6	99.21%
T3617	Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically i...
T12574	PTC299	1256565-36-2	99.19%
T12574	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA trans...
T9121	AG-636	1623416-31-8	99.19%
T9121	AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
T0647	Tryptamine	61-54-1	99.16%
T0647	Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It ...
T15022	CVT-10216	1005334-57-5	99.16%
T15022	CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC5...
T15550	IDH-305	1628805-46-8	99.13%
T15550	IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor. IDH-305 shows greater than 200 fold selectivity for mutant IDH1 isoforms vs....
T26397	6PGD-IN-S3	5539-66-2	99.12%
T26397	6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).
T0293	Metyrapone	54-36-4	99.12%
T0293	Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the ...
T6293	Mycophenolate Mofetil	128794-94-5	99.11%
T6293	Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate ...
T3494	LW6	934593-90-5	99.10%
T3494	LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.
TN1829	Kakkalide	58274-56-9	99.1%
TN1829	Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects.