Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T77579	JC2-11	937820-89-8	98.6%
T77579	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
T0245	RS 61443	115007-34-6	98.58%
T0245	RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)
T13100	TC HSD 21	330203-01-5	98.5%
T13100	TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).
T77576	17β-HSD10-IN-1	2316765-78-1	98.47%
T77576	17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of A...
T11765	KPLH1130	906669-07-6	98.43%
T11765	KPLH1130, a specific pyruvate dehydrogenase kinase (PDK) inhibitor, enhances glucose tolerance in mice fed a high-fat diet (HFD). It effectively hinders macropha...
T23533	WIN 18446	1477-57-2	98.41%
T23533	inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
T5S0620	3-Dehydrotrametenolic acid	29220-16-4	98.39%
T5S0620	1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new...
T2901	Daidzin	552-66-9	98.28%
T2901	Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T73446	BI‑3231	2894848-07-6	98.2%
T73446	BI‑3231 is a selective and potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study...
T1979	AVN-944	297730-17-7	98.19%
T1979	AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T1809	AGI-6780	1432660-47-3	98.19%
T1809	AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
T3175	LDHA-IN-4	1370290-34-8	98.17%
T3175	LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells b...
T9003	CVT-11127	1018674-83-3	98.15%
T9003	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
T3542	BVT-14225	376638-65-2	98.14%
T3542	BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).
T4382	Proguanil hydrochloride	637-32-1	98.13%
T4382	Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguani...
T1717	Alpha-Mangostin	6147-11-1	98.12%
T1717	alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
T67875	DHODH-IN-23	1346705-53-0	98.1%
T67875	DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
T67832	ALDH2 modulator 1	1629615-99-1	98.07%
T67832	ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
T6384	Ammonium Glycyrrhizinate	1407-03-0	98.05%
T6384	Ammonium Glycyrrhizinate (Glycyram) inhibits the cytopathology and growth of several unrelated DNA/RNA viruses.
T10384	Farudodstat	1035688-66-4	98.03%
T10384	Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be...