T77606 |
WAY-311610
|
314051-55-3
|
98.01%
|
|
WAY-311610 is an 11β-hydroxysteroid dehydrogenase HSD11B1 inhibitor that inhibits the 11β-HSD1 enzyme with an IC = 0.34 μM.It can be used to study neuropathic pa...
|
T0256 |
Citric acid trilithium salt tetrahydrate
|
6080-58-6
|
98%
|
|
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiat...
|
T4S0878 |
Prunetin
|
552-59-0
|
98%
|
|
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin media...
|
T3044 |
(E/Z)-Teriflunomide
|
108605-62-5
|
98%
|
|
(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.
|
T7400 |
RRX-001
|
925206-65-1
|
98%
|
|
RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
|
T8332 |
Bipenquinate
|
96201-88-6
|
97.77%
|
|
Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.
|
T16161 |
Mutant IDH1 inhibitor
|
1429180-08-4
|
97.72%
|
|
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
|
T1818 |
Tenovin-6
|
1011557-82-6
|
97.71%
|
|
Tenovin-6 is a p53 transcriptional activity agonist.
|
T2S2211 |
Tenuifoliside C
|
139726-37-7
|
97.64%
|
|
Tenuifoliside C, isolated from polygala tenuifolia willd, is a target lactate dehydrogenase inhibitor. It significantly inhibits chlorzoxazone 6-hydroxylation ca...
|
T4295 |
(R)-GNE-140
|
2003234-63-5
|
97.32%
|
|
(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.
|
T2104 |
AGI-5198
|
1355326-35-0
|
97.3%
|
|
AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).
|
T11024 |
DHODH-IN-15
|
1364791-88-7
|
97.26%
|
|
DHODH-IN-15 is the hydroxyfuran analogue of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. D...
|
T4778 |
3-Hydroxybenzaldehyde
|
100-83-4
|
97.05%
|
|
3-Hydroxybenzaldehyde is a compound useful in organic synthesis.
|
T1608 |
ADH-1 trifluoroacetate
|
1135237-88-5
|
96.64%
|
|
ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ...
|
T22336 |
Galloflavin
|
568-80-9
|
96.24%
|
|
Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer...
|
T1374 |
2-Pyridinecarbohydrazide
|
1452-63-7
|
95.52%
|
|
2-Pyridinecarbohydrazide (2-Picolinyl hydrazide) is an effective inhibitor of Catalase-peroxidase-NAPDH.
|
T10148 |
4-Hydroxynonenal
|
75899-68-2
|
95.12%
|
|
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
|
T0054 |
Disulfiram
|
97-77-8
|
95%
|
|
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutel...
|
T14884 |
CBR-5884
|
681159-27-3
|
100%
|
|
CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer...
|
T25006 |
AGI-14100
|
1448346-43-7
|
100%
|
|
AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
|