T11799 |
L-745870 hydrochloride
|
1173023-36-3
|
97.36%
|
|
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagon...
|
T0076 |
Paliperidone
|
144598-75-4
|
96.98%
|
|
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically,...
|
T35841 |
5-Benzyloxygramine
|
1453-97-0
|
96.33%
|
|
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1].
5-benzyloxygramine stabili...
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T15461 |
Halopemide
|
59831-65-1
|
96.29%
|
|
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used ...
|
T12352 |
Oxidopamine hydrochloride
|
28094-15-7
|
96.17%
|
|
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.
|
T24047 |
Etilevodopa hydrochloride
|
39740-30-2
|
95.00%
|
|
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
|
T0185 |
Escitalopram
|
128196-01-0
|
94.62%
|
|
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
|
T14083 |
Abaperidone
|
183849-43-6
|
94.35%
|
|
Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperid...
|
T13164 |
Tipepidine hydrochloride
|
1449686-84-3
|
100.00%
|
|
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effec...
|
T67729 |
UCM-1306
|
2258608-78-3
|
100%
|
|
UCM-1306 is a potent and orally active allosteric modulator (PAM) of human dopamine D1 receptor. UCM-1306 could increase the maximal effect of endogenous dopamin...
|
T1175 |
Bromopride
|
4093-35-0
|
100%
|
|
Bromopride (Valopride) is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not avai...
|
T6398 |
Azaperone
|
1649-18-9
|
100%
|
|
Azaperone (Fluoperidol) is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer ...
|
T1201 |
Sulpiride
|
15676-16-1
|
100%
|
|
Sulpiride (Aiglonyl) is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
|
T1180 |
Blonanserin
|
132810-10-7
|
100%
|
|
Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerab...
|
T7943 |
Fluphenazine decanoate
|
5002-47-1
|
100%
|
|
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.
|
T8136 |
Perospirone hydrochloride
|
129273-38-7
|
100%
|
|
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A recept...
|
T26834 |
BL-1020 Mesylate
|
916898-61-8
|
100%
|
|
BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activit...
|
T1222 |
Trifluoperazine dihydrochloride
|
440-17-5
|
100%
|
|
Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
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T8382 |
Cariprazine hydrochloride
|
1083076-69-0
|
100%
|
|
Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)
|
T1336 |
Benztropine mesylate
|
132-17-2
|
100%
|
|
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
|