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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T1336 Benztropine mesylate 132-17-2 100%
Benztropine mesylate
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
T0811 Amisulpride 71675-85-9 100%
Amisulpride
Amisulpride (DAN 2163) (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for ...
T5135 Flupentixol dihydrochloride 2413-38-9 100%
Flupentixol dihydrochloride
Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.
T6241 Quetiapine hemifumarate 111974-72-2 100%
Quetiapine hemifumarate
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I dep...
T0351 Risperidone 106266-06-2 100%
Risperidone
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
T0068 Fluphenazine dihydrochloride 146-56-5 100%
Fluphenazine dihydrochloride
Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metab...
T0806 Flunarizine dihydrochloride 30484-77-6 100%
Flunarizine dihydrochloride
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihy...
T68076L Fosopamine(HCl) 135962-35-5 100%
Fosopamine(HCl)
Fosopamine(HCl) is a DRDs agonist that can be used to study hypertension.
T12489L Pimethixene maleate 13187-06-9 100%
Pimethixene maleate
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
T30098 Aplindore Fumarate 189681-71-8 100%
Aplindore Fumarate
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors,...
T1735 Lurasidone hydrochloride 367514-88-3 100%
Lurasidone hydrochloride
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotoni...
T4081 MPTP hydrochloride 23007-85-4 100%
MPTP hydrochloride
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, whic...
T1211 Levosulpiride 23672-07-3
Levosulpiride
Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.
T0043 Octodrine 543-82-8
Octodrine
Octodrine (2-Amino-6-methylheptane) is a local anesthetic and vasoconstrictor, but mainly as a pharmaceutical intermediate of Octamylamine.
T22817 GSK 789472 hydrochloride 1257326-24-1
GSK 789472 hydrochloride
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.
T4007 Eticlopride hydrochloride 97612-24-3
Eticlopride hydrochloride
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).
T5009 Trimethobenzamide hydrochloride 554-92-7
Trimethobenzamide hydrochloride
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
T8702 SKF-83566 99295-33-7
SKF-83566
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
T4616 Metoclopramide 364-62-5
Metoclopramide
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the ...
T3426 Bacoside A 11028-00-5
Bacoside A
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
Benztropine mesylate
T1336
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISE...
Amisulpride
T0811
Amisulpride (DAN 2163) (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for ...
Flupentixol dihydrochloride
T5135
Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.
Quetiapine hemifumarate
T6241
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I dep...
Risperidone
T0351
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
Fluphenazine dihydrochloride
T0068
Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metab...
Flunarizine dihydrochloride
T0806
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihy...
Fosopamine(HCl)
T68076L
Fosopamine(HCl) is a DRDs agonist that can be used to study hypertension.
Pimethixene maleate
T12489L
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2...
Aplindore Fumarate
T30098
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors,...
Lurasidone hydrochloride
T1735
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotoni...
MPTP hydrochloride
T4081
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, whic...
Levosulpiride
T1211
Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.
Octodrine
T0043
Octodrine (2-Amino-6-methylheptane) is a local anesthetic and vasoconstrictor, but mainly as a pharmaceutical intermediate of Octamylamine.
GSK 789472 hydrochloride
T22817
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.
Eticlopride hydrochloride
T4007
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).
Trimethobenzamide hydrochloride
T5009
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
SKF-83566
T8702
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
Metoclopramide
T4616
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the ...
Bacoside A
T3426
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
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TargetMol