T22019 |
ABT 724 trihydrochloride
|
587870-77-7
|
99.72%
|
|
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively)....
|
T0162 |
Quetiapine
|
111974-69-7
|
99.71%
|
|
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism ...
|
T1327 |
Nortriptyline hydrochloride
|
894-71-3
|
99.71%
|
|
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
|
T2574 |
Alizapride hydrochloride
|
59338-87-3
|
99.71%
|
|
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
|
T15117 |
Didesmethyl cariprazine
|
839712-25-3
|
99.70%
|
|
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is ...
|
T5387 |
LP-211
|
1052147-86-0
|
99.7%
|
|
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
|
T4008 |
Metergoline
|
17692-51-2
|
99.7%
|
|
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
|
T0074 |
Chlorprothixene
|
113-59-7
|
99.69%
|
|
Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.
|
T2306 |
Brexpiprazole
|
913611-97-9
|
99.69%
|
|
Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.
|
T2631 |
WAY-100635 Maleate
|
1092679-51-0
|
99.68%
|
|
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
|
T19680 |
Zotepine
|
26615-21-4
|
99.67%
|
|
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3...
|
T10758L |
Centanafadine hydrochloride
|
923981-14-0
|
99.66%
|
|
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC...
|
T10168 |
5-HT1A modulator 1
|
142477-34-7
|
99.66%
|
|
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
|
T0783 |
Mianserin hydrochloride
|
21535-47-7
|
99.63%
|
|
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of...
|
T5380 |
Ansofaxine hydrochloride
|
916918-84-8
|
99.63%
|
|
Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).
|
T1090 |
Perphenazine
|
58-39-9
|
99.63%
|
|
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
|
T2546 |
Pimozide
|
2062-78-4
|
99.63%
|
|
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
|
T21782 |
A 77636 hydrochloride
|
145307-34-2
|
99.62%
|
|
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows anti...
|
T39429 |
AHN 1-055 hydrochloride
|
202646-03-5
|
99.60%
|
|
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).
|
T3086 |
Mesoridazine Besylate
|
32672-69-8
|
99.58%
|
|
Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. ...
|