Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.

Cat. No.	Product name	CAS No.	Purity
T2546	Pimozide	2062-78-4	99.63%
T2546	Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
T21782	A 77636 hydrochloride	145307-34-2	99.62%
T21782	A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows anti...
T39429	AHN 1-055 hydrochloride	202646-03-5	99.60%
T39429	AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).
T0991	Desipramine hydrochloride	58-28-6	99.58%
T0991	Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervou...
T3086	Mesoridazine Besylate	32672-69-8	99.58%
T3086	Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. ...
TN6552	5,7-Dimethoxyluteolin	90363-40-9	99.56%
TN6552	5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.
T12207	NEO 376	496921-73-4	99.56%
T12207	NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
T0031L2	Ziprasidone	146939-27-7	99.53%
T0031L2	Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T24885	Tiospirone	87691-91-6	99.52%
T24885	Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in...
T33816	Ordopidine	871351-60-9	99.52%
T33816	Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopi...
T2190	Methiothepin mesylate	74611-28-2	99.51%
T2190	Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.
T9081	FAUC 346	474432-65-0	99.51%
T9081	FAUC 346 is a highly selective D3 partial agonist with EC50 of 1.5 nM.
T13110	Tedatioxetine hydrobromide	960151-65-9	99.50%
T13110	Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) is a serotonin-norepinephrine-dopamine reuptake inhibitor and an antagonist of 5-HT2A, 5-HT2C, 5-HT3, and α...
T21337	Lurasidone	367514-87-2	99.5%
T21337	Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6....
T2132	Buspirone hydrochloride	33386-08-2	99.5%
T2132	Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T27677	JNJ-37822681	935776-74-2	99.48%
T27677	JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor.
T10232	Acetophenazine dimaleate	5714-00-1	99.48%
T10232	Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.
T10705	CCG 203769	410074-60-1	99.46%
T10705	CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
T32737	Liafensine	1198790-53-2	99.46%
T32737	Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dop...
T23483	U 99194 maleate	234757-41-6	99.45%
T23483	U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.