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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN1081 Hirsuteine 35467-43-7 99.36%
Hirsuteine
Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channe...
T16472 Pericyazine 2622-26-6 99.36%
Pericyazine
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to t...
T22530 6-Chloromelatonin 63762-74-3 99.36%
6-Chloromelatonin
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for the same presynaptic melatonin receptor sites in the rabbi...
T28167 NGB 2904 189060-98-8 99.35%
NGB 2904
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4...
T0031L Ziprasidone hydrochloride 122883-93-6 99.34%
Ziprasidone hydrochloride
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic acti...
T23232 Remoxipride hydrochloride 73220-03-8 99.32%
Remoxipride hydrochloride
Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, >100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoce...
T0137 Mirtazapine 85650-52-8 99.3%
Mirtazapine
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asy...
T12383 PD 168568 dihydrochloride 1782532-06-2 99.27%
PD 168568 dihydrochloride
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
T7632 Veralipride 66644-81-3 99.21%
Veralipride
Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.
T12510 PNU-177864 hydrochloride 1783978-03-9 99.20%
PNU-177864 hydrochloride
PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor. PNU-177864 hydrochloride is structurally consistent with a ...
T6835 Fenoldopam mesylate 67227-57-0 99.19%
Fenoldopam mesylate
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through a...
T70302 Fallypride 166173-78-0 99.17%
Fallypride
Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.
T9228 Propionylpromazine hydrochloride 7681-67-6 99.17%
Propionylpromazine hydrochloride
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.
T3369 Nuciferine 475-83-2 99.16%
Nuciferine
Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine re...
T0074L Chlorprothixene hydrochloride 6469-93-8 99.16%
Chlorprothixene hydrochloride
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrener...
T0719 Tetrabenazine 58-46-8 99.13%
Tetrabenazine
Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake i...
T33711L Nolomirole HCl 138531-51-8 99.12%
Nolomirole HCl
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study m...
T0445 Promethazine 60-87-7 99.11%
Promethazine
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
T34616 Seridopidine 883631-51-4 99.11%
Seridopidine
Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.
T6988 SKF 38393 hydrochloride 62717-42-4 99.1%
SKF 38393 hydrochloride
SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist.
Hirsuteine
TN1081
Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channe...
Pericyazine
T16472
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to t...
6-Chloromelatonin
T22530
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for the same presynaptic melatonin receptor sites in the rabbi...
NGB 2904
T28167
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4...
Ziprasidone hydrochloride
T0031L
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic acti...
Remoxipride hydrochloride
T23232
Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, >100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoce...
Mirtazapine
T0137
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asy...
PD 168568 dihydrochloride
T12383
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
Veralipride
T7632
Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.
PNU-177864 hydrochloride
T12510
PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor. PNU-177864 hydrochloride is structurally consistent with a ...
Fenoldopam mesylate
T6835
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through a...
Fallypride
T70302
Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.
Propionylpromazine hydrochloride
T9228
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.
Nuciferine
T3369
Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine re...
Chlorprothixene hydrochloride
T0074L
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrener...
Tetrabenazine
T0719
Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake i...
Nolomirole HCl
T33711L
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study m...
Promethazine
T0445
Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
Seridopidine
T34616
Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.
SKF 38393 hydrochloride
T6988
SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist.
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TargetMol