Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No.	Product name	CAS No.
T5873	2,6-Dihydroxybenzoic acid	303-07-1
T5873	2,6-Dihydroxybenzoic acid, a secondary metabolite derived from salicylic acid, undergoes hydrolyzation by liver enzymes as part of phase I metabolism.
TN7108	Urolithin C	165393-06-6
TN7108	Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T2830	Betulinic acid	472-15-1
T2830	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
T4882	Arabinose	147-81-9
T4882	Arabinose (DL-Arabinose), also known as (+/-)-arabinose or aloe sugar. Arabinose has been primarily detected in feces. Within the cell, Arabinose is primarily lo...
T8192	Pentacosanoic acid	506-38-7
T8192	Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids.
T4762	L-Pipecolic acid	3105-95-1
T4762	L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as ...
T4925	Thiamine monophosphate chloride (dihydrate)	273724-21-3
T4925	Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability
T4806	H-D-Trp-OH	153-94-6
T4806	H-D-Trp-OH (D-Tryptophan) is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the ma...
T4717	25-Hydroxycholesterol	2140-46-7
T4717	25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase ...
T4760	KSD 2405	620-24-6
T4760	KSD 2405 (3-Hydroxybenzyl alcohol) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or beige to brown...
T7357	(S)-b-aminoisobutyric acid	4249-19-8
T7357	(S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of valine and thymine.
T4829	3-Hydroxyphenylacetic acid	621-37-4
T4829	3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxypheny...
T7682	Asymmetric dimethylarginine	30315-93-6
T7682	Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T4786	D-Ribose(mixture of isomers)	50-69-1
T4786	D-Ribose(mixture of isomers) (D-(-)-Ribose), commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential ...
T9344	3-Amino-2-oxazolidinone	80-65-9
T9344	3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone . It is always be detected as a indicator of furazolidone residues in vivo.
T9299	D-Leucine	328-38-1
T9299	D-Leucine ((R)-Leucine) potently terminates seizures even after the onset of seizure activity. D-leucine reduces long-term potentiation but had no effect on basa...
T4798	N-Acetyl-L-leucine	1188-21-2
T4798	N-Acetylleucine belongs to the class of organic compounds known as leucine and derivatives. Leucine and derivatives are compounds containing leucine or a derivat...
T4810	Pyrocatechuic acid	303-38-8
T4810	Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion.
T8273	4,6-Dioxoheptanoic acid	51568-18-4
T8273	4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis.
TQ0024	3-Hydroxyglutaric acid	638-18-6
TQ0024	3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.