Home Tools
Log in
Cart

Epigenetic Reader Domain

Epigenetic reader domains can be thought of as effector proteins that recognize and are recruited to specific epigenetic marks.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2120 I-BET151 1300031-49-5 99.03%
I-BET151
I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
T6668 SGC-CBP30 1613695-14-9 99.03%
SGC-CBP30
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
T3697 3',6-Disinapoylsucrose 139891-98-8 99.02%
3',6-Disinapoylsucrose
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
T13890 SMARCA-BD ligand 1 for Protac dihydrochloride 2369053-68-7 99.01%
SMARCA-BD ligand 1 for Protac dihydrochloride
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
T11136 E-7386 1799824-08-0 99%
E-7386
E-7386 is an oral active CBP/ -catenin modulator.
T14776 BRD4 Inhibitor-10 1660117-38-3 98.98%
BRD4 Inhibitor-10
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
T31224 Piflufolastat 1423758-00-2 98.98%
Piflufolastat
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat ...
T1516 Curcumin 458-37-7 98.98%
Curcumin
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide...
T5425 ML367 381168-77-0 98.97%
ML367
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitor...
T5362 Y06036 1832671-96-1 98.95%
Y06036
Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).
T9399 Menin-MLL inhibitor 20 2448173-47-3 98.89%
Menin-MLL inhibitor 20
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
T2379 UNC1215 1415800-43-9 98.87%
UNC1215
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold ...
T8495 Alobresib 1637771-14-2 98.87%
Alobresib
Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.
T12338 OXFBD04 2231747-03-6 98.84%
OXFBD04
OXFBD04 is a potent and selective BRD4 inhibitor (IC50= 166 nM). OXFBD04 is a potent BET bromodomain ligand and exhibits additional modest affinity for the CREBB...
T6389 Anacardic Acid 16611-84-0 98.84%
Anacardic Acid
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial...
T1906 Molibresib 1260907-17-2 98.82%
Molibresib
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).
T4495 DBET1 1799711-21-9 98.79%
dBET1
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apopt...
T6786 BI-9564 1883429-22-8 98.77%
BI-9564
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
T1972 GSK-5959 901245-65-6 98.77%
GSK-5959
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel...
T14685 BMS-986158 1800340-40-2 98.77%
BMS-986158
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple ...
I-BET151
T2120
I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
SGC-CBP30
T6668
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
3',6-Disinapoylsucrose
T3697
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
SMARCA-BD ligand 1 for Protac dihydrochloride
T13890
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
E-7386
T11136
E-7386 is an oral active CBP/ -catenin modulator.
BRD4 Inhibitor-10
T14776
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
Piflufolastat
T31224
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat ...
Curcumin
T1516
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide...
ML367
T5425
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitor...
Y06036
T5362
Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).
Menin-MLL inhibitor 20
T9399
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
UNC1215
T2379
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold ...
Alobresib
T8495
Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.
OXFBD04
T12338
OXFBD04 is a potent and selective BRD4 inhibitor (IC50= 166 nM). OXFBD04 is a potent BET bromodomain ligand and exhibits additional modest affinity for the CREBB...
Anacardic Acid
T6389
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial...
Molibresib
T1906
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).
dBET1
T4495
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apopt...
BI-9564
T6786
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
GSK-5959
T1972
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel...
BMS-986158
T14685
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple ...
1 2 3 4 5 6 7 8 9 10 11 12 13 14
TargetMol