T2120 |
I-BET151
|
1300031-49-5
|
99.03%
|
|
I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
|
T6668 |
SGC-CBP30
|
1613695-14-9
|
99.03%
|
|
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
|
T3697 |
3',6-Disinapoylsucrose
|
139891-98-8
|
99.02%
|
|
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
|
T13890 |
SMARCA-BD ligand 1 for Protac dihydrochloride
|
2369053-68-7
|
99.01%
|
|
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
|
T11136 |
E-7386
|
1799824-08-0
|
99%
|
|
E-7386 is an oral active CBP/ -catenin modulator.
|
T14776 |
BRD4 Inhibitor-10
|
1660117-38-3
|
98.98%
|
|
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
|
T31224 |
Piflufolastat
|
1423758-00-2
|
98.98%
|
|
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat ...
|
T1516 |
Curcumin
|
458-37-7
|
98.98%
|
|
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide...
|
T5425 |
ML367
|
381168-77-0
|
98.97%
|
|
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitor...
|
T5362 |
Y06036
|
1832671-96-1
|
98.95%
|
|
Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).
|
T9399 |
Menin-MLL inhibitor 20
|
2448173-47-3
|
98.89%
|
|
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
|
T2379 |
UNC1215
|
1415800-43-9
|
98.87%
|
|
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold ...
|
T8495 |
Alobresib
|
1637771-14-2
|
98.87%
|
|
Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.
|
T12338 |
OXFBD04
|
2231747-03-6
|
98.84%
|
|
OXFBD04 is a potent and selective BRD4 inhibitor (IC50= 166 nM). OXFBD04 is a potent BET bromodomain ligand and exhibits additional modest affinity for the CREBB...
|
T6389 |
Anacardic Acid
|
16611-84-0
|
98.84%
|
|
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial...
|
T1906 |
Molibresib
|
1260907-17-2
|
98.82%
|
|
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).
|
T4495 |
DBET1
|
1799711-21-9
|
98.79%
|
|
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apopt...
|
T6786 |
BI-9564
|
1883429-22-8
|
98.77%
|
|
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
|
T1972 |
GSK-5959
|
901245-65-6
|
98.77%
|
|
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel...
|
T14685 |
BMS-986158
|
1800340-40-2
|
98.77%
|
|
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple ...
|