Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. THYMOPENTIN is...
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloprotea...
Liquiritigenin, a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist. |
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively). |
||Endoxifen E-isomer hydrochloride
Endoxifen, a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM). |
β-thujaplicin can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activit...
Kaempferide triglycoside inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not mediated by l...
Bavachin is a phytoestrogen that activates the estrogen receptors ERα and ERβ. |
WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM). |
AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity. |
Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor ...
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respect...
S-equol is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with...
Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively. |
Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vul...
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells,respectively. |
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. |
Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents. |
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist. |
Tamoxifen is an antagonist of the estrogen receptor in breast tissue. |
Tamoxifen is an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). |
PHTPP is a selective Erβ antagonist. |
<p>Afimoxifene, a tamoxifen metabolite, is estrogen receptor antagonist (IC50: 3.3 nM). It also increases CRISPR/Cas9-mediated editing frequency.</p> |
Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the...
GDC-0810 is a selective estrogen receptor degrader (IC50: 0.7 nM). |
Nestoron, a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM). |
GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand |
H3B-5942 belongs to a class of ERα antagonists referred to as selective estrogen receptor covalent antagonists (SERCA). |
||PROTAC ERRα ligand 2
PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM) |
Gestrinone is a synthetic androgen receptor agonist and ER and progesterone receptor antagonist used to treat endometriosis. It inhibits leiomyoma cells with an...
DPN is an selective agonist of estrogen receptor β (ERβ) . |
Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ. |
Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα. |
Lasofoxifene Tartrate is a third-generation, non-steroidal selective estrogen receptor modulator. |
27-Hydroxycholesterol is a selective modulator of estrogen receptor and an agonist of the liver X receptor. |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive ...
Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist |
Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens. |
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects. |
Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. |
Standard reference |
Segetalin A has estrogen-like activity. |
||Allura Red AC
Allura Red AC and amaranth are very important food azo dyes used in food, drug, paper, cosmetic and textile industries. |
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likel...
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-infla...
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as ...
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM) |
NXT629 is a selective and competitive antagonist of PPAR-α(human PPARα with an IC50 of 77 nM). |
OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ. |
Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor. |