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Estrogen Receptor/ERR

The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones.There are three human estrogen related receptors:ERRα,ERRβand ERRγ .
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T12654 (Rac)-Acolbifene 151533-34-5 98.18%
(Rac)-Acolbifene
(Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogen...
T10239 Acolbifene 182167-02-8 98.17%
Acolbifene
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ER...
T20744 Nylestriol 39791-20-3 98.16%
Nylestriol
Nylestriol (LY 49825) is an agonist of estrogen receptor.
T15364 G-1 881639-98-1 98.14%
G-1
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
T15249 Estrogen receptor modulator 1 63676-22-2 98.14%
Estrogen receptor modulator 1
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active a...
T12832 Amcenestrant 2114339-57-8 98.13%
Amcenestrant
Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC...
T2810 (20S)-Protopanaxatriol 34080-08-5 98.12%
(20S)-Protopanaxatriol
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid re...
T11236 Giredestrant tartrate 2407529-33-1 98.01%
Giredestrant tartrate
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestran...
T7313 Enclomiphene citrate 7599-79-3 98%
Enclomiphene citrate
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
T7299 β-Estradiol 17-acetate 1743-60-8 98%
β-Estradiol 17-acetate
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a metabolite of estradiol.
T5624 Bisphenol B 77-40-7 98%
Bisphenol B
Bisphenol B has a binding affinity for estrogen receptors.
T5531 GSK-4716 101574-65-6 98%
GSK-4716
GSK4716 is an ERRβ/γ agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand
T3665 Tectoridin 611-40-5 98%
Tectoridin
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, a...
T0040 Quinestrol 152-43-2 98%
Quinestrol
Quinestrol (Ethinylestradiol 3-cyclopentyl ether) is a synthetic estrogen, applied in hormone replacement therapy, and occasionally to use in cancer and prostate...
T5835 PROTAC ERRα ligand 2 2306388-57-6 98%
PROTAC ERRα ligand 2
PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)
T2544 Bazedoxifene acetate 198481-33-3 98%
Bazedoxifene acetate
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).
T5S0543 Isocurcumenol 24063-71-6 98%
Isocurcumenol
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T15788 LSZ-102 2135600-76-7 97.84%
LSZ-102
LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.
T2882 Genistin 529-59-9 97.65%
Genistin
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflamm...
T8370 GSK5182 877387-37-6 97.63%
GSK5182
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
(Rac)-Acolbifene
T12654
(Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogen...
Acolbifene
T10239
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ER...
Nylestriol
T20744
Nylestriol (LY 49825) is an agonist of estrogen receptor.
G-1
T15364
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
Estrogen receptor modulator 1
T15249
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active a...
Amcenestrant
T12832
Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC...
(20S)-Protopanaxatriol
T2810
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid re...
Giredestrant tartrate
T11236
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestran...
Enclomiphene citrate
T7313
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
β-Estradiol 17-acetate
T7299
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a metabolite of estradiol.
Bisphenol B
T5624
Bisphenol B has a binding affinity for estrogen receptors.
GSK-4716
T5531
GSK4716 is an ERRβ/γ agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand
Tectoridin
T3665
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, a...
Quinestrol
T0040
Quinestrol (Ethinylestradiol 3-cyclopentyl ether) is a synthetic estrogen, applied in hormone replacement therapy, and occasionally to use in cancer and prostate...
PROTAC ERRα ligand 2
T5835
PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)
Bazedoxifene acetate
T2544
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).
Isocurcumenol
T5S0543
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
LSZ-102
T15788
LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.
Genistin
T2882
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflamm...
GSK5182
T8370
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
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TargetMol