Estrogen/progestogen Receptor

Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPER (GPR30), which is a member of the rhodopsin-like family of G protein-coupled receptors.The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone.

Cat. No.	Product name	CAS No.	Purity
T3717	Hinokitiol	499-44-5	99.78%
T3717	Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the a...
T0384	Estradiol benzoate	50-50-0	99.76%
T0384	Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexu...
TN1148	Isopsoralenoside	905954-18-9	99.75%
TN1148	Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.
TN1052	Lindleyin	59282-56-3	99.74%
TN1052	Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
T1102	Mifepristone	84371-65-3	99.74%
T1102	Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T0593	XCT790	725247-18-7	99.74%
T0593	XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).
T1284	Megestrol acetate	595-33-5	99.72%
T1284	Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic pr...
T3325	Liquiritigenin	578-86-9	99.7%
T3325	Liquiritigenin (4',7-Dihydroxyflavanone), a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist.
T2567	Etonogestrel	54048-10-1	99.69%
T2567	Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.
T3806	Kaempferide	491-54-3	99.66%
T3806	kaempferide (4'-Methylkaempferol) inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not media...
T4281	Endoxifen	110025-28-0	99.66%
T4281	(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It ...
T0188	Fluticasone (propionate)	80474-14-2	99.65%
T0188	Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid recep...
T0870	Altrenogest	850-52-2	99.61%
T0870	Altrenogest (Allyltrenbolone)(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone.
T3378	Alpha-Estradiol	57-91-0	99.61%
T3378	Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia.
T6491	(-)-(S)-Equol	531-95-3	99.61%
T6491	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by hu...
T1688	Pregnanediol	80-92-2	99.6%
T1688	Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane...
T4420	4-Hydroxytamoxifen	68047-06-3	99.56%
T4420	4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen h...
T3958	WAY-200070	440122-66-7	99.46%
T3958	WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).
T15191	PROTAC ERRα ligand 1	1264754-13-3	99.45%
T15191	PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).
T1261	Medroxyprogesterone Acetate	71-58-9	99.45%
T1261	Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective ...