Estrogen/progestogen Receptor

Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPER (GPR30), which is a member of the rhodopsin-like family of G protein-coupled receptors.The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone.

Cat. No.	Product name	CAS No.	Purity
T6683	STF-62247	315702-99-9	99.45%
T6683	STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
T33876L1	Panomifene TFA		99.39%
T33876L1	Panomifene TFA（GYKl13504 TFA） is a small molecule antagonist of ERs with anticancer activity that can be used to study breast cancer and musculoskeletal diseases...
T14987	CMP8	851107-28-3	99.38%
T14987	CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM...
T4388	PHTPP	805239-56-9	99.37%
T4388	PHTPP is a selective ERβ antagonist.
T1048	Estradiol	50-28-2	99.35%
T1048	Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradi...
T1514	Norethindrone	68-22-4	99.33%
T1514	Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ...
TQ0274	27-Hydroxycholesterol	20380-11-4	99.31%
TQ0274	27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
T0168	Estradiol (cypionate)	313-06-4	99.2%
T0168	Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor.
T6533	Hexestrol	84-16-2	99.2%
T6533	Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
T1216	Diethylstilbestrol	56-53-1	99.13%
T1216	Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.
T17252	SIM-688	796854-35-8	99.12%
T17252	SIM-688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells).
T2177	Kaempferol	520-18-3	99.11%
T2177	Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, ...
T13443	(R)-Equol	221054-79-1	99.04%
T13443	(R)-Equol ((+)-Equol) is an ERα and ERβ agonist with Kis of 27.4 and 15.4 nM, respectively.
T11399	Giredestrant	1953133-47-5	98.96%
T11399	Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has an...
T0345	Estropipate	7280-37-7	98.95%
T0345	Estropipate (Piperazine estrone sulfate) is a natural estrogenic substance composed of estrone sulfate and piperazine.
T13674	Elacestrant	722533-56-4	98.92%
T13674	Elacestrant (RAD1901) with IC50s of 48 and 870 nM for ERα and ERβ, respectively.Elacestrant is an orally available selective estrogen receptor degrader .
T2231	Estradiol dipropionate	113-38-2	98.89%
T2231	Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a synthetic ester, specifically the 3, 17-dipropanoyl ester, of the natural estrogen, estradiol.
T2569	Chlorotrianisene	569-57-3	98.88%
T2569	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen r...
T2973	Astragaloside IV	84687-43-4	98.85%
T2973	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metall...
T7644	DPN	1428-67-7	98.85%
T7644	DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .