T67747 |
CB2R/FAAH modulator-3
|
2876918-67-9
|
99.02%
|
|
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are...
|
T16515 |
PF 750
|
959151-50-9
|
98.83%
|
|
PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
|
T68492 |
AM 374
|
86855-26-7
|
98.39%
|
|
AM 374 (HDSF) is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC 50 value of 13 nM. AM 374 can be used for the resear...
|
T5357 |
ARN272
|
488793-85-7
|
98.23%
|
|
ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).
|
T15802 |
LY2183240
|
874902-19-9
|
98.17%
|
|
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 27...
|
T11256 |
FAAH inhibitor 1
|
326866-17-5
|
98.05%
|
|
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.
|
T6043 |
PF-3845
|
1196109-52-0
|
98%
|
|
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
|
T6714 |
URB-597
|
546141-08-6
|
97.84%
|
|
URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.
|
T2859 |
Biochanin A
|
491-80-5
|
97.1%
|
|
Biochanin A (4-Methylgenistein) is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Biochanin A is a natura...
|
T67896 |
CB2R/FAAH modulator-1
|
928892-60-8
|
100%
|
|
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
|
T3S2105 |
N-Benzylpalmitamide
|
74058-71-2
|
98%
|
|
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the tre...
|
TN1965 |
N-Benzyllinolenamide
|
883715-18-2
|
98%
|
|
N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).
|
T4323 |
PF-04457845
|
1020315-31-4
|
98%
|
|
PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).
|
T23119 |
Palmitoylisopropylamide
|
189939-61-5
|
98%
|
|
Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.
|
T28353 |
PDP-EA
|
861891-72-7
|
98%
|
|
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.
|
T1325 |
Carprofen
|
53716-49-7
|
98%
|
|
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.
|