TQ0235 |
AC710
|
1351522-04-7
|
98%
|
|
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).
|
T6S0033 |
Crotonoside
|
1818-71-9
|
98%
|
|
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestin...
|
T73549 |
RSH-7
|
2764609-97-2
|
98%
|
|
RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing apoptos...
|
T6982 |
SGI-7079
|
1239875-86-5
|
98%
|
|
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR...
|
T10531 |
BGB-102
|
807640-87-5
|
98%
|
|
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular deg...
|
T6028 |
PF 477736
|
952021-60-2
|
98%
|
|
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CS...
|
T14072 |
A-443654
|
552325-16-3
|
98%
|
|
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
|
T2272 |
BPR1J-097
|
1327167-19-0
|
98%
|
|
BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).
|
T2066 |
Quizartinib
|
950769-58-1
|
98%
|
|
Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
|
T4261 |
BPR1J-097 hydrochloride (1327167-19-0(free base))
|
T4261
|
98%
|
|
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
|
T2051 |
SKLB4771
|
1370256-78-2
|
98%
|
|
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
|
T0093 |
Sorafenib tosylate
|
475207-59-1
|
98%
|
|
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
|