Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.

Cat. No.	Product name	CAS No.	Purity
T0334	Rosiglitazone	122320-73-4	99.87%
T0334	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidi...
T9073	SRS16-86	1793052-96-6	99.85%
T9073	SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
T2O2733	L-Cystine	56-89-3	99.85%
T2O2733	L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cyste...
T4360	ML385	846557-71-9	99.85%
T4360	ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhib...
T60168	NCOA4 - 9a	2650557-72-3	99.84%
T60168	NCOA4 - 9a is a ferroptosis inhibitor.
TQ0211	Brusatol	14907-98-3	99.82%
TQ0211	Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
T3S1447	Arteannuin B	50906-56-4	99.8%
T3S1447	1. Arteannuin B has potent antimalarial activity.
T1710	Trolox	53188-07-1	99.8%
T1710	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T1637	Deferoxamine Mesylate	138-14-7	99.8%
T1637	Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
T6646	Rosiglitazone hydrochloride	302543-62-0	99.79%
T6646	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
T8970	ML162	1035072-16-2	99.78%
T8970	ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
T36404L	PRLX-93936 HCL	1094210-96-4	99.78%
T36404L	PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T6192	Alogliptin	850649-61-5	99.77%
T6192	Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9....
T7530	PD146176	4079-26-9	99.77%
T7530	PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses...
T1644	Dopamine hydrochloride	62-31-7	99.76%
T1644	Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and ...
T64357	FA16		99.75%
T64357	FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibit...
T11631	IFSP1	150651-39-1	99.74%
T11631	iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse huma...
T1847	Necrostatin-1	4311-88-0	99.74%
T1847	Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin...
T1297	Eugenol	97-53-0	99.72%
T1297	Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immun...
T5687	WITHAFERIN A	5119-48-2	99.71%
T5687	WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or...